Results 241 to 250 of about 360,378 (339)
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen+9 more
wiley +1 more source
Analysis of volatile organic compounds in exhaled breath of blood cancer patients identifies products of lipid peroxidation as biomarkers for lymphoma detection. [PDF]
Stiekema LCA+8 more
europepmc +1 more source
Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao+8 more
wiley +1 more source
Targeting oxidative stress-induced lipid peroxidation enhances podocyte function in cystinosis. [PDF]
Berlingerio SP+14 more
europepmc +1 more source
EVIDENCE FOR LIPID PEROXIDATION DURING MODERATE EXERCISE IN MAN
P-O. Balke+2 more
openalex +1 more source
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen+14 more
wiley +1 more source
Susceptibility of Mitophagy-Deficient Tumors to Ferroptosis Induction by Relieving the Suppression of Lipid Peroxidation. [PDF]
Liu S+13 more
europepmc +1 more source
Peroxide-decomposing activities of antarctic krill lipids and certain other oils.
Jong‐Ho Lee+2 more
openalex +2 more sources