Results 311 to 320 of about 360,378 (339)
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Lipid peroxidation in homocysteinaemia
Journal of Inherited Metabolic Disease, 1992Homocysteinaemia due to cystathione synthase deficiency (CSD: McKusick 236200) is a rare autosomal recessive inborn error of methionine metabolism. The most life-threatening complications caused by CSD are thromboembolism and vascular abnormalities.
R.A. de Abreu +7 more
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Peroxidation of liposomal lipids
European Biophysics Journal, 2007Free radicals, formed via different mechanisms, induce peroxidation of membrane lipids. This process is of great importance because it modifies the physical properties of the membranes, including its permeability to different solutes and the packing of lipids and proteins in the membranes, which in turn, influences the membranes' function. Accordingly,
Ilya Pinchuk +2 more
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Critical Reviews in Oncology/Hematology, 1993
Lipid peroxidation, firstly described as a mechanism of lipid deterioration by chemists, is now considered as a major mechanism of elementary lesion in living cells, and in many cases the major cause for their death. In living animals, it was firstly described to increase after irradiation [23,32,252] and then in vitamin E deficiency [57,258,259].
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Lipid peroxidation, firstly described as a mechanism of lipid deterioration by chemists, is now considered as a major mechanism of elementary lesion in living cells, and in many cases the major cause for their death. In living animals, it was firstly described to increase after irradiation [23,32,252] and then in vitamin E deficiency [57,258,259].
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Mechanisms of lipid peroxidation
Journal of Free Radicals in Biology & Medicine, 1985This article provides an overview of how peroxidation of unsaturated lipids takes place and how it can be measured. Several different aspects of free-radical-mediated lipid peroxidation are discussed, including: the catalytic role of chelated iron and other redox metal ions; induction by reducing agents such as superoxide, ascorbate, and xenobiotic ...
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1997
Publisher Summary This chapter presents the fundamental characteristics of oxygen radical-induced lipid peroxidation (LP) as they relate to the pathophysiology of focal and global cerebral ischemia and subarachnoid hemorrhage (SAH). There is extensive biochemical, physiological, and pharmacological evidence in support of an important role of LP in ...
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Publisher Summary This chapter presents the fundamental characteristics of oxygen radical-induced lipid peroxidation (LP) as they relate to the pathophysiology of focal and global cerebral ischemia and subarachnoid hemorrhage (SAH). There is extensive biochemical, physiological, and pharmacological evidence in support of an important role of LP in ...
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Lipid peroxidation in spermatozoa
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1973Ram spermatozoa produce aerobically an organic peroxide which can be determined quantitatively by the thiobarbituric acid reaction. The reaction is more intense in spermatozoa that have been stored at 5°C. Cold shock and homogenization release from spermatozoa a substance, presumably a lipid, which provides the substrate for peroxidation.
Thaddeus Mann, Richard A. L. Jones
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Inhibition of lipid peroxidation
Biological Trace Element Research, 1997Lipid peroxy radicals (ROO.) were detected by electron spin resonance (ESR) at low temperature after formation by addition of H2O2 into a suspension of mice lymphocytes. If lymphocytes were treated with selenomethionine (Se-Met) prior to addition of H2O2, ROO. formation was inhibited in a fashion that was dependent on Se-Met concentration. Formation of
Dijiang Wen +5 more
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Lipid peroxidation in mitochondria
Free Radical Biology and Medicine, 1988The present review article takes into consideration the most important aspects of lipid peroxidation in mitochondria. Firstly the various ways by which lipid peroxidation is induced and the relevant mechanisms are described and discussed. After examining the major effects of lipid peroxidation on mitochondrial enzymes and bioenergetic functions, some ...
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Pathological aspects of lipid peroxidation
Free Radical Research, 2010Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular and cellular dysfunction that plays a major role in ageing and most age-related and oxidative stress-related diseases. The current evidence for the implication of LPO in pathological processes is discussed in this review.
Nègre-Salvayre, Anne +24 more
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Lipid peroxidation in the pathogenesis of neuroborreliosis
Free Radical Biology and Medicine, 2016This study analyzed the onset of lipid peroxidation (LPO) in neuroborreliosis and the effects of ceftriaxone therapy on LPO. Twenty-two patients with early neuroborreliosis and 22 healthy subjects were studied. LPO in the cerebrospinal fluid (CSF), as well as the plasma and urine was estimated by the levels of reactive aldehydes: 4-hydroxynonenal (4 ...
Wojciech Łuczaj +7 more
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