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Mechanisms of lipid peroxidation

Journal of Free Radicals in Biology & Medicine, 1985
This article provides an overview of how peroxidation of unsaturated lipids takes place and how it can be measured. Several different aspects of free-radical-mediated lipid peroxidation are discussed, including: the catalytic role of chelated iron and other redox metal ions; induction by reducing agents such as superoxide, ascorbate, and xenobiotic ...
Albert W Girotti
exaly   +3 more sources

Lipid peroxidation in mitochondria

Free Radical Biology and Medicine, 1988
The present review article takes into consideration the most important aspects of lipid peroxidation in mitochondria. Firstly the various ways by which lipid peroxidation is induced and the relevant mechanisms are described and discussed. After examining the major effects of lipid peroxidation on mitochondrial enzymes and bioenergetic functions, some ...
A Bindoli
exaly   +3 more sources

Lipid peroxidation and lipid peroxide detected by chemiluminescence

Free Radical Biology and Medicine, 1987
This article emphasizes the advantages of using a luminescence spectrometer based on photon counting techniques for the detection of lipid peroxidation. An overview is presented of how chemiluminescence can be stimulated in the luminol-cytochrome c heme peptide system as an assay for lipid hydroperoxides.
T, Iwaoka, F, Tabata, T, Takahashi
openaire   +2 more sources

Lipid peroxides and thrombosis

Bulletin of Experimental Biology and Medicine, 1979
In incubation of rabbit platelets with ADF, adrenalin, serotonin and thrombin the level of hydroxyperoxides serotonin and thrombin the level of hydroxyperoxides serotonin and thrombin the level of hydroxyperoxides they show, determined with respect to malonic dialdehyde, rises simultaneously with the enhancement of aggregation activity.
A A, Kubatiev, S V, Andreev
openaire   +2 more sources

Measurement of Lipid Peroxidation

Current Protocols in Toxicology, 1999
AbstractThere is currently considerable interest in what is termed “oxidative stress,” or the oxidation of biological macromolecules, with emphasis on its involvement in various diseases and toxicities and methods to limit either its occurrence or effects.
C A, Reilly, S D, Aust
openaire   +2 more sources

Lipid peroxidation in erythrocytes

Chemistry and Physics of Lipids, 1987
Erythrocytes might be expected to be highly susceptible to peroxidation. Their membranes are rich in polyunsaturated fatty acids; they are continuously exposed to high concentrations of oxygen; and they contain a powerful transition metal catalyst. In fact, autoxidation is held in check in vivo by extremely efficient protective antioxidant mechanisms ...
M R, Clemens, H D, Waller
openaire   +2 more sources

Lipid peroxidation in neurodegeneration

Clinica Chimica Acta, 2019
Neurodegenerative diseases have great social and economic impact and cause millions of deaths every year. The potential molecular mechanisms in these pathologies have been widely studied and implicate lipid peroxidation as an important factor in the development of neurodegenerative disorders such as Alzheimer's, Parkinson's and Huntington's diseases ...
Carmen Peña-Bautista   +3 more
openaire   +2 more sources

Lipid peroxidation in homocysteinaemia

Journal of Inherited Metabolic Disease, 1992
Homocysteinaemia due to cystathione synthase deficiency (CSD: McKusick 236200) is a rare autosomal recessive inborn error of methionine metabolism. The most life-threatening complications caused by CSD are thromboembolism and vascular abnormalities.
H J, Blom   +7 more
openaire   +2 more sources

Measurement of Lipid Peroxidation

Free Radical Research, 1998
Lipid peroxidation results in the formation of conjugated dienes, lipid hydroperoxides and degradation products such as alkanes, aldehydes and isoprostanes. The approach to the quantitative assessment of lipid peroxidation depends on whether the samples involve complex biological material obtained in vivo, or whether the samples involve relatively ...
K, Moore, L J, Roberts
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Lipid peroxidation and cancer

Critical Reviews in Oncology/Hematology, 1993
Lipid peroxidation, firstly described as a mechanism of lipid deterioration by chemists, is now considered as a major mechanism of elementary lesion in living cells, and in many cases the major cause for their death. In living animals, it was firstly described to increase after irradiation [23,32,252] and then in vitamin E deficiency [57,258,259].
openaire   +2 more sources

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