Results 61 to 70 of about 369,467 (261)

Lipid peroxidation of immune cells in cancer

Frontiers in Immunology
Growing evidence indicates that cellular metabolism is a critical determinant of immune cell viability and function in antitumor immunity and lipid metabolism is important for immune cell activation and adaptation to the tumor microenvironment (TME ...
Liuling Xiao, Miao Xian, Chuanchao Zhang, Qi Guo, Qing Yi   +4 more
doaj   +1 more source

Peroxiredoxin 6 phospholipid hydroperoxidase activity in the repair of peroxidized cell membranes

Redox Biology, 2018
Although lipid peroxidation associated with oxidative stress can result in cellular death, sub-lethal lipid peroxidation can gradually resolve with return to the pre-exposure state.
Aron B. Fisher, Jose P. Vasquez-Medina, Chandra Dodia, Elena M. Sorokina, Jian-Qin Tao, Sheldon I. Feinstein   +5 more
doaj   +1 more source

CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease

Redox Biology, 2020
The oxidative degradation of lipids has been shown to be implicated in the progression of several neurodegenerative diseases and modulating lipid peroxidation may be efficacious for treating Alzheimer’s disease (AD).
Gamze Ates, Joshua Goldberg, Antonio Currais, Pamela Maher   +3 more
doaj   +1 more source

Association between lipid peroxidation biomarkers and microRNA expression profiles

Redox Biology, 2022
Background: In-vitro and animal studies demonstrate that epigenetic regulation may play an important role in lipid peroxidation. No human study to date has directly evaluated microRNAs (miRNAs), as epigenetic modulators, in relation to systemic levels of
Yingya Zhao, Marina S. Nogueira, Ginger L. Milne, Xingyi Guo, Hui Cai, Qing Lan, Nathaniel Rothman, Qiuyin Cai, Yu-Tang Gao, Qingxia Chen, Xiao-Ou Shu, Gong Yang   +11 more
doaj   +1 more source

Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved [PDF]

, 2011
Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and experimental evidence supports the hypothesis that heme iron present in meat promotes colorectal cancer ...
Bingham, Chen, Clinton, Cross, Cummings, de Vogel, Denis E. Corpet, Douglass, Fabrice H.F. Pierre, Grant, Leuratti, Marnett, Mirvish, Nadia M. Bastide, Nauss, Nutter, Parnaud, Pierre, Pierre, Sandhu, Sawa, Schwartz, Sesink, Shuker, Sinha   +24 more
core   +4 more sources

Exogenous Iron Induces Mitochondrial Lipid Peroxidation, Lipofuscin Accumulation, and Ferroptosis in H9c2 Cardiomyocytes

Biomolecules
Lipid peroxidation plays an important role in various pathologies and aging, at least partially mediated by ferroptosis. The role of mitochondrial lipid peroxidation during ferroptosis remains poorly understood.
Konstantin G. Lyamzaev, He Huan, Alisa A. Panteleeva, Ruben A. Simonyan, Armine V. Avetisyan, Boris V. Chernyak   +5 more
doaj   +1 more source

Montmorency cherries reduce the oxidative stress and inflammatory responses to repeated days high-intensity stochastic cycling [PDF]

, 2014
This investigation examined the impact of Montmorency tart cherry concentrate (MC) on physiological indices of oxidative stress, inflammation and muscle damage across 3 days simulated road cycle racing.
Alessio, Bitsch, Delgado, Emma Stevenson, Felgines, Fossati, Gareth Davison, Girotti, Glyn Howatson, Goldfarb, Ian Walshe, Kelley, Phillip Bell, Phillips, Sies, Starkie   +15 more
core   +2 more sources

Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain

Acta Neuropathologica Communications, 2022
Lipid peroxidation is a process of oxidative degradation of cellular lipids that is increasingly recognized as an important factor in the pathogenesis of neurodegenerative diseases.
YuHong Fu, Ying He, Katherine Phan, Surabhi Bhatia, Russell Pickford, Ping Wu, Nicolas Dzamko, Glenda M. Halliday, Woojin Scott Kim   +8 more
doaj   +1 more source

Calcium Carbonate Suppresses Haem Toxicity Markers without Calcium Phosphate Side Effect on Colon Carcinogenesis [PDF]

, 2010
Red meat intake is associated with increased risk of colorectal cancer. We have previously shown that haemin, haemoglobin and red meat promote carcinogen-induced preneoplastic lesions, aberrant crypt foci, in the colon of rats.
Belbraouet, Bruce, Bull, Cross, Denis E. Corpet, Diane Bahuaud, Fabrice H. F. Pierre, Karkare, Nathalie Naud, Ossama Allam, Pierre, Sesink, Sinha, Sylviane Taché, Van den Berg   +14 more
core   +4 more sources

The mechanism of NADPH-dependent lipid peroxidation. The propagation of lipid peroxidation.

Journal of Biological Chemistry, 1979
NADPH-dependent lipid peroxidation occurs in two distinct sequential radical steps. The first step, initiation, is the ADP-perferryl ion-catalyzed formation of low levels of lipid hydroperoxides. The second step, propagation, is the iron-catalyzed breakdown of lipid hydroperoxides formed during initiation generating reactive intermediates and products ...
F O O'Neal, John A. Buege, B A Svingen, Steven D. Aust   +3 more
openaire   +2 more sources