Results 71 to 80 of about 1,632,742 (358)

Meat crust as a novel food ingredient to regulate lipid peroxidation and oxidative stress

Current Research in Food Science
Pan Fry (PF) is a common heating treatment however, there is limited data on meat oxidation after PF using direct contact with an uncoated iron pan. After PF, a crust is formed, and in this study, we aim to evaluate the potential anti-oxidation and anti ...
Eylon Asido, Haim Zeigerman, Michal Verman, Nurit Argov-Argaman, Joseph Kanner, Oren Tirosh   +5 more
doaj   +1 more source

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

Advanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri, Xinan Huang, Emanuel Lörtscher, Cora‐Ann Schoenenberger, Cornelia G. Palivan   +4 more
wiley   +1 more source

Deuterated Linoleic Acid Attenuates the RBC Storage Lesion in a Mouse Model of Poor RBC Storage

Frontiers in Physiology, 2022
Background: Long-chain polyunsaturated fatty acids (PUFAs) are important modulators of red blood cell (RBC) rheology. Dietary PUFAs are readily incorporated into the RBC membrane, improving RBC deformability, fluidity, and hydration.
Christopher Y. Kim, Hannah Johnson, Sandy Peltier, Steven L. Spitalnik, Eldad A. Hod, Richard O. Francis, Krystalyn E. Hudson, Elizabeth F. Stone, Dominique E. Gordy, Xiaoyun Fu, James C. Zimring, Pascal Amireault, Pascal Amireault, Paul W. Buehler, Robert B. Wilson, Angelo D’Alessandro, Mikhail S. Shchepinov, Tiffany Thomas   +17 more
doaj   +1 more source

Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]

, 2012
The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Birke, Kerstin, Burger, Johannes, Welge-Lussen, Ulrich, Yu, Alice L.   +3 more
core   +3 more sources

Regulation of lipid peroxidation and ferroptosis in diverse species

Genes & Development, 2018
This review by Conrad et al. reviews the functions and regulation of lipid peroxidation, ferroptosis, and the antioxidant network in diverse species, including humans, other mammals and vertebrates, plants, invertebrates, yeast, bacteria, and archaea ...
M. Conrad, V. Kagan, H. Bayır, G. Pagnussat, B. Head, M. Traber, B. Stockwell   +6 more
semanticscholar   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Lipid peroxidation of immune cells in cancer

Frontiers in Immunology
Growing evidence indicates that cellular metabolism is a critical determinant of immune cell viability and function in antitumor immunity and lipid metabolism is important for immune cell activation and adaptation to the tumor microenvironment (TME ...
Liuling Xiao, Miao Xian, Chuanchao Zhang, Qi Guo, Qing Yi   +4 more
doaj   +1 more source

CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease

Redox Biology, 2020
The oxidative degradation of lipids has been shown to be implicated in the progression of several neurodegenerative diseases and modulating lipid peroxidation may be efficacious for treating Alzheimer’s disease (AD).
Gamze Ates, Joshua Goldberg, Antonio Currais, Pamela Maher   +3 more
doaj   +1 more source

Association between lipid peroxidation biomarkers and microRNA expression profiles

Redox Biology, 2022
Background: In-vitro and animal studies demonstrate that epigenetic regulation may play an important role in lipid peroxidation. No human study to date has directly evaluated microRNAs (miRNAs), as epigenetic modulators, in relation to systemic levels of
Yingya Zhao, Marina S. Nogueira, Ginger L. Milne, Xingyi Guo, Hui Cai, Qing Lan, Nathaniel Rothman, Qiuyin Cai, Yu-Tang Gao, Qingxia Chen, Xiao-Ou Shu, Gong Yang   +11 more
doaj   +1 more source

Iron toxicity, lipid peroxidation and ferroptosis after intracerebral haemorrhage

Stroke and vascular neurology, 2019
Intracerebral haemorrhage (ICH) is a devastating type of stroke with high mortality and morbidity. However, we have few options for ICH therapy and limited knowledge about post-ICH neuronal death and related mechanisms.
Jie-ru Wan, Honglei Ren, Jian Wang
semanticscholar   +1 more source