Results 111 to 120 of about 57,019 (310)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Hepatoprotective efficacy of low molecular weight chicken intestine peptide against acute alcohol-induced liver injury

open access: yesFood Science and Human Wellness
Food-derived bioactive peptides exhibit good health-promoting effects. In this study, low molecular weight chicken intestine peptide (CIP) below 2 kDa is prepared through trypsin hydrolysis of chicken intestine and ultrafiltration, and the ...
Changyu Yan   +17 more
doaj   +1 more source

Research advances of ferroptosis in renal diseases

open access: yesLinchuang shenzangbing zazhi, 2021
Ferroptosis is characterized by intracellular iron overload and an accumulation of reactive oxygen species leading to lipid peroxidation.Although ferroptosis is more extensively discussed for acute kidney injury and renal cell carcinoma, its potential ...
Yu Peng, Wang Ting-ting, Liu Hong-bao
doaj  

Lipoxygenase-mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3 [PDF]

open access: yes, 2017
学位記番号 ...
Shintoku, Ryosuke   +2 more
core  

Mass Spectrometric Analysis of Oxidized Eicosapentaenoic Acid Sodium Salt [PDF]

open access: yes, 2013
Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid (PUFA) with 20 carbon atoms and 5 carbon-carbon double bonds. Mammalian cells cannot synthesize long chain PUFAs such as EPA de novo, and, thus, the most effective way to enrich cells ...
Jordan, Kelsey D., Upmacis, Rita K.
core   +3 more sources

VALUATION OF FREE RADICALS ACTIVITY BY LIPID PEROXIDATION, IN NEONATAL PERIOD. 1431 [PDF]

open access: bronze, 1996
Francisco Paulo Martins Rodrigues   +2 more
openalex   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu   +21 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad   +3 more
wiley   +1 more source

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