Results 211 to 220 of about 87,561 (363)

Tackling Allergic Airway Inflammation with Organic Sheet‐Like Nanoplatforms by Targeted Elimination of Epithelial Small Extracellular Vesicles

Advanced Science, EarlyView.
In this work, “inorganic‐free” nanosheets, named PNSE are developed using template‐based synthesis technology. The functionalized organic nanosheets exhibit low cytotoxicity, mild protein adsorption, and potent binding efficacy to epithelial sEVs.
Zhaoxu Tu, Junyan Lin, Zhixin Li, Yuefei Zhu, Changyi Xu, Zihan Qiu, Qiumin Wang, Yang Ye, Yihui Wen, Jian Li, Kam W. Leong, Weiping Wen   +11 more
wiley   +1 more source

ACSL4 at the helm of the lipid peroxidation ship: a deep-sea exploration towards ferroptosis. [PDF]

Front Pharmacol
Jiang Y, Zhang M, Sun M.
europepmc   +1 more source

STUDIES ON DRUG METABOLISM XXXVIII PEROXIDATION OF LIPIDS AND ACTIVITIES OF DRUG METABOLIZING ENZYMES IN LIVER MICROSOMES (III)

, 1973
Mitsukazu Kitada, Tetsuya Kamataki, Yoshiko Arai, Haruo Kitagawa   +3 more
openalex   +1 more source

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

Advanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu, Xiaobei Wang, Parker Mathews, Shaima Jabbar, Min Zhang, Haim Moskowitz, Wei Duan, David P. Nichols, George William Schaaf, John D. Olson, Andrew N. Macintyre, J. Daniel Bourland, Ivan Spasojevic, Jen‐Tsan Ashley Chi, Joel Ross, Nelson Chao, J. Mark Cline, Peter B. Heifetz, Yubin Kang   +18 more
wiley   +1 more source

Targeting ALOX5 ameliorates renal tubular injury in ischemia-reperfusion-induced acute kidney injury via inhibition of ferroptosis. [PDF]

Commun Biol
Huang L, Tang Q, Li G, Hou Y, Chen S, Yao Q, Luo Y, Xiong L, Zhang Y, Yang H, Wang L, Li G, Li Y, Feng Y.   +13 more
europepmc   +1 more source

Individual Differences in the Occurrence of a Lipid Peroxidation Inhibitor in Rat Liver Soluble Fraction

, 1975
Tetsuya Kamataki, Kazuo Aikawa, Naok̆i Ozawa, Haruo Kitagawa   +3 more
openalex   +1 more source

Unveiling Macrophage Content as a Predictive Biomarker for Intraoperative ICG Imaging Efficacy in Lung Cancer

Advanced Science, EarlyView.
Indocyanine Green (ICG)‐guided lung cancer surgery efficacy varies significantly among patients. This study identifies tumor macrophage content as a predictive biomarker. Macrophages are primary ICG reservoirs, storing seven‐fold more ICG than cancer cells.
Yue Yan, Jiahui Mi, Yun Li, Guanchao Jiang, Yimeng Zhang, Yanguo Liu, Hui Zhao, Jianfeng Li, Xing Yang, Jun Wang, Fan Yang, Kezhong Chen, Yiguang Wang, Jian Zhou   +13 more
wiley   +1 more source

Dysregulated bile acid metabolism drives lipid peroxidation and ferroptosis in NAFLD: therapeutic potential for traditional Chinese medicine. [PDF]

Front Pharmacol
Liu J, Li F, Zeng Q, Hu W, Yang L, Luo S, Li D, Deng Y.   +7 more
europepmc   +1 more source

Effect of phosphate on ferrous ion- and ascorbate-induced lipid peroxidations of rat ascites hepatoma cells (AH-130) and mitochondria

, 1976
Gonosuke Hashimoto, Michio Yamamoto, Masatada Tanabe, Kaname AONO, Goki Yamamoto   +4 more
openalex   +2 more sources

Microwave‐Activated Bacterial Biorobot for Multimodal Cancer Therapy

Advanced Science, EarlyView.
An Escherichia coli bacterial biorobot is engineered for localized microwave activation in cancer therapy. Upon activation at tumor sites, the biorobot releases glucose oxidase, inducing tumor cell death via glucose depletion and H2O2 generation catalyzed by Cu2O.
Huilan Zhuang, Yongjian Zhang, Yajuan Fu, Dangjin Ke, Qi Chen, Sijie Shao, Panpan Xue, Yuanchun Chen, Xuemei Zeng, Shuangqian Yan   +9 more
wiley   +1 more source