Results 321 to 330 of about 87,561 (363)
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Inhibition of lipid peroxidation
Biological Trace Element Research, 1997Lipid peroxy radicals (ROO.) were detected by electron spin resonance (ESR) at low temperature after formation by addition of H2O2 into a suspension of mice lymphocytes. If lymphocytes were treated with selenomethionine (Se-Met) prior to addition of H2O2, ROO. formation was inhibited in a fashion that was dependent on Se-Met concentration. Formation of
Dijiang Wen +5 more
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Lipid peroxidation in mitochondria
Free Radical Biology and Medicine, 1988The present review article takes into consideration the most important aspects of lipid peroxidation in mitochondria. Firstly the various ways by which lipid peroxidation is induced and the relevant mechanisms are described and discussed. After examining the major effects of lipid peroxidation on mitochondrial enzymes and bioenergetic functions, some ...
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Pathological aspects of lipid peroxidation
Free Radical Research, 2010Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular and cellular dysfunction that plays a major role in ageing and most age-related and oxidative stress-related diseases. The current evidence for the implication of LPO in pathological processes is discussed in this review.
Nègre-Salvayre, Anne +24 more
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Lipid peroxidation in the pathogenesis of neuroborreliosis
Free Radical Biology and Medicine, 2016This study analyzed the onset of lipid peroxidation (LPO) in neuroborreliosis and the effects of ceftriaxone therapy on LPO. Twenty-two patients with early neuroborreliosis and 22 healthy subjects were studied. LPO in the cerebrospinal fluid (CSF), as well as the plasma and urine was estimated by the levels of reactive aldehydes: 4-hydroxynonenal (4 ...
Wojciech Łuczaj +7 more
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Lipid Peroxidation in Diabetes Mellitus
Antioxidants & Redox Signaling, 2005There is considerable evidence that hyperglycemia represents the main cause of complications of diabetes mellitus (DM), and oxidative stress resulting from increased generation of reactive oxygen species plays a crucial role in their pathogenesis. In fact, in the absence of an appropriate response from endogenous antioxidant mechanisms, the redox ...
DAVI', Giovanni, FALCO A, PATRONO C.
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Rabbit liver microsomal lipid peroxidation The effect of lipid on the rate of peroxidation
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1982Rat and rabbit liver microsomes catalyze an NADPH-cytochrome P-450 reductase-dependent peroxidation of endogenous lipid in the presence of the chelate, ADP-Fe3+. Although liver microsomes from both species contain comparable levels of NADPH-cytochrome P-450 reductase and cytochrome P-450, the rate of lipid peroxidation (assayed by malondialdehyde and ...
Ming Tien, Steven D. Aust
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[30] Microsomal lipid peroxidation
1978Publisher Summary This chapter discusses microsomal lipid peroxidation. Lipid peroxidation is a complex process known to occur in both plants and animals. It involves the formation and propagation of lipid radicals, the uptake of oxygen, a rearrangement of the double bonds in unsaturated lipids, and the eventual destruction of membrane lipids ...
Steven D. Aust, John A. Buege
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Hydrogen peroxide and hematin in microsomal lipid peroxidation
Journal of Inorganic Biochemistry, 1981Lipids of rat liver microsomes underwent peroxidation with production of malondialdehyde in the presence of H2O2 and hematin. Rates of peroxidation of 27-33 nmol of MDA formed/mg of microsomal protein/30 min were measured with 5 mM H2O2 and 10 microM hematin at 22 degrees C. Histidine (0.01 M) caused a 55% inhibition.
URSINI, FULVIO +4 more
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Lipid peroxidation in tumour cells
Free Radical Biology and Medicine, 1988Several studies point to the existence of a disturbance in the metabolism of the reactive species of oxygen in cancer cells. Based on this evidence, and in particular on a characteristic behaviour of tumour membrane lipids, namely their growth-related resistance to oxy-radical-induced peroxidation, a sequence of events is outlined that could ...
L. Masotti +2 more
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Effects of Melanins on Lipid Peroxidation
Applied Biochemistry and Microbiology, 2001Effects of melanins obtained from cultured Cladosporium cladosporidae fungi and Alpha grape on Fe(2+)-induced, Fe(2+)-ascorbate-induced, and NADPH-induced lipid peroxidation in rat liver, brain, and eye were studied. Melanins were shown to inhibit the accumulation of lipid peroxidation products in vitro.
Byshneva Ln, Senchuk Vv
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