Results 91 to 100 of about 69,365 (334)

Glycosphingolipid GM3 is localized in both exoplasmic and cytoplasmic leaflets of Plasmodium falciparum malaria parasite plasma membrane

open access: yesScientific Reports, 2021
Lipid rafts, sterol-rich and sphingolipid-rich microdomains on the plasma membrane are important in processes like cell signaling, adhesion, and protein and lipid transport.
Shiomi Koudatsu   +8 more
doaj   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

open access: yesAdvanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao   +6 more
wiley   +1 more source

Intercellular Horizontal Transfer of TXNDC5 mRNA via Extracellular Vesicles Contributes to Tumor‐Associated Macrophage‐Mediated Prostate Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
This study investigates the role of M2 macrophage‐derived extracellular vesicles (M2 EVs) in prostate cancer (PCa) metastasis. Mechanistically, M2 EVs horizontally transfer TXNDC5 mRNA to PCa cells, where the molecule induces the mesenchymal‐like state (MLS), enhancing PCa migration and invasion.
Cong Hu   +14 more
wiley   +1 more source

Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity [PDF]

open access: yes, 2009
L1-CAM (L1 cell-adhesion molecule), or more simply L1, plays an important role in the progression of human carcinoma. Overexpression promotes tumour-cell invasion and motility, growth in nude mice and tumour metastasis.
Altevogt, Peter   +6 more
core  

Review of presentations at the 6th European Lupus Meeting 3-5 March 2005. [PDF]

open access: yes, 2005
The 6th European Lupus Meeting was held at the Royal College of Physicians of London and was attended by 450 delegates. The conference brought together leading speakers from Europe and North America who reviewed current knowledge and exciting new ...
Bowman, SJ   +3 more
core   +1 more source

Lipid Rafts: Membrane Triage Centers [PDF]

open access: yesJournal of Investigative Dermatology, 2006
Both biochemical and live cell imaging studies suggest the existence of lipid rafts, specialized membrane microdomains that promote interaction among signaling molecules. Although their composition is still poorly understood, these highly dynamic domains are enriched in cholesterol, sphingolipids, and particular groups of proteins.
Wang, Xiao-qi, Paller, Amy S.
openaire   +2 more sources

Anesthetics interacting with lipid rafts

open access: yesEuropean Journal of Pharmaceutical Sciences, 2013
The exact mechanism by which anesthetics induce cell membrane-mediated modifications is still an open question. Although the fluidization effect of the anesthetic molecules on the cellular membrane is widely recognized, it is not known if anesthetics show any preference for specific membrane domains, namely the lipid rafts.
Cátia, Bandeiras   +4 more
openaire   +2 more sources

Cholesterol, lipid rafts, and disease [PDF]

open access: yesJournal of Clinical Investigation, 2002
Lipid rafts are dynamic assemblies of proteins and lipids that float freely within the liquid-disordered bilayer of cellular membranes but can also cluster to form larger, ordered platforms. Rafts are receiving increasing attention as devices that regulate membrane function in eukaryotic cells.
Simons, K., Ehehalt, R.
openaire   +3 more sources

Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages

open access: yesHaematologica, 2010
Background Expression of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and is decreased by hepcidin. We previously showed that ferroportin is present in specific cell surface domains suggestive of lipid ...
Anne Auriac   +2 more
doaj   +1 more source

10-Gingerol Targets Lipid Rafts Associated PI3K/Akt Signaling in Radio-Resistant Triple Negative Breast Cancer Cells

open access: yesMolecules, 2020
10-Gingerol is a major phenolic lipid found in the rhizomes of ginger (Zingiber officinale). Being amphiphilic in nature, phenolic lipids have the ability to incorporate into cell membranes and modulate membrane properties.
Meran Keshawa Ediriweera   +3 more
doaj   +1 more source

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