Results 161 to 170 of about 1,129,041 (391)
Dissecting the role of the Golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface [PDF]
, 2000 Sanna Heino +5 more
openalex +1 more source
Lipid rafts and their analytical methods.
Folia Pharmacologica Japonica, 2003 Microdomains in cell membranes consist of caveolae and lipid rafts, in which cholesterol, glycolipids, and sphingomyelin are concentrated. While caveolae are relatively stable because caveolin, an integral protein, supports the structure, lipid rafts are unstable, being dynamically produced and degraded.
Satoko Ohkubo, Norimichi Nakahata
openaire +3 more sources
Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities
Advanced Science, EarlyView.The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley +1 more source
MoleculesThe molecular events of protein misfolding and self-aggregation of tau and amylin are associated with the progression of Alzheimer’s and diabetes, respectively. Recent studies suggest that tau and amylin can form hetero-tau-amylin oligomers. Those hetero-
Natalia Santos +4 more
doaj +1 more source
Cell Communication and Signaling, 2011 Background Lipid rafts present on the plasma membrane play an important role in spatiotemporal regulation of cell signaling. Physical and chemical characterization of lipid raft size and assessment of their composition before, and after cell stimulation ...
Kennedy Colleen +2 more
doaj +1 more source
Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast [PDF]
, 2000 Michel Bagnat +4 more
openalex +1 more source
Advanced Science, EarlyView.This review summarizes recent advances in cGAS‐STING agonist‐based nanotherapeutics for cancer combination therapy. It explores nanoparticle‐mediated delivery strategies, underlying molecular mechanisms, and combinatorial applications with chemotherapy, radiotherapy, targeted therapy, phototherapy, sonodynamic therapy, and immunotherapy.
Zhaomeng Wang +3 more
wiley +1 more source
Lipid-dependent Targeting of G Proteins into Rafts [PDF]
, 2000 Serge Moffett +2 more
openalex +1 more source
Aggregate, EarlyView.Schematic illustration of labeling live Treponema pallidum using an activated alkyne‐modified AIE chromophore via catalyst‐free bioorthogonal reaction. ABSTRACT Treponema pallidum (T. pallidum) causes syphilis, a sexually transmitted disease that leads to multi‐organ complications and even death. The lack of technology for tracing live T.
Jialin Huang +9 more
wiley +1 more source
Lipids in Health and DiseaseLipid rafts are specialized microdomains within cellular membranes enriched with cholesterol and sphingolipids that play key roles in cellular organization, signaling, and homeostasis.
Mohamad Warda +5 more
doaj +1 more source