Clostridium innocuum, an emerging pathogen that induces lipid raft-mediated cytotoxicity. [PDF]
Wu HY+10 more
europepmc +1 more source
A P-glikoprotein membrán mikrokörnyezete és működésének gátolhatósága modulátor és antitest együttes alkalmazásával = P-glycoprotein membrane microenviroment and inhibition of pumping by the combined application of modulators and specific antibody [PDF]
A multidrog rezisztencia hátterében gyakran a P-glikoprotein (Pgp) pumpa működése áll, melynek gátlására jelentős erőfeszítések történnek világszerte. Az UIC2 antitest a fehérjét katalitikus ciklusa egy fázisában ismeri fel, és ott blokkolja.
Bacsó, Zsolt+3 more
core
Variational Methods for Biomolecular Modeling
Structure, function and dynamics of many biomolecular systems can be characterized by the energetic variational principle and the corresponding systems of partial differential equations (PDEs).
A Ivankin+114 more
core +1 more source
Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization [PDF]
Concepción Gómez‐Moutón+9 more
openalex +1 more source
Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li+6 more
wiley +1 more source
Raft Busters: A Molecular Role for DHA in Biological Membranes? [PDF]
poster abstractDietary consumption of fish oils rich in omega-3 polyunsaturated fatty acids (n-3 PUFAs), such as docosahexaenoic acid (DHA, 22:6), has a wide variety of health benefits. However, a complete molecular mechanism is yet to be elucidated. One
Bittman, Robert+5 more
core
Rapid Cycling of Lipid Raft Markers between the Cell Surface and Golgi Complex [PDF]
Benjamin J. Nichols+7 more
openalex +1 more source
The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons during rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic lipids and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production of ...
Rose Follis+2 more
wiley +1 more source
Rafting on the Evidence for Lipid Raft-like Domains as Hubs Triggering Environmental Toxicants' Cellular Effects. [PDF]
Marques-da-Silva D, Lagoa R.
europepmc +1 more source