N-(3-Oxododecanoyl)-Homoserine Lactone Induces Intestinal Barrier Damage in Piglets via the Lipid Raft-Mediated Apoptosis Pathway. [PDF]
Yang Y +7 more
europepmc +1 more source
This study investigates the role of M2 macrophage‐derived extracellular vesicles (M2 EVs) in prostate cancer (PCa) metastasis. Mechanistically, M2 EVs horizontally transfer TXNDC5 mRNA to PCa cells, where the molecule induces the mesenchymal‐like state (MLS), enhancing PCa migration and invasion.
Cong Hu +14 more
wiley +1 more source
The transmembrane domain of the desmosomal cadherin desmoglein-1 governs lipid raft association to promote desmosome adhesive strength. [PDF]
Zimmer SE +3 more
europepmc +1 more source
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz +10 more
wiley +1 more source
Microarray-Based Methodology for Lipid Profiling, Enzymatic Activity, And Binding Assays in Printed Lipid Raft Membranes from Astrocytes and Neurons. [PDF]
Sánchez-Sánchez L +4 more
europepmc +1 more source
Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao +4 more
wiley +1 more source
Retraction Note: Disruption of lipid-raft localized Gαs/tubulin complexes by antidepressants: a unique feature of HDAC6 inhibitors, SSRI and tricyclic compounds. [PDF]
Singh H +3 more
europepmc +1 more source
Abstract Emerging evidence highlights the central role of peripheral immune–metabolic regulation in the pathogenesis of Alzheimer's disease and related dementias (ADRD). Among peripheral organs, the spleen has gained increasing attention as a critical immune–metabolic hub linking systemic homeostasis to central neurodegeneration.
Jingsi Yan +7 more
wiley +1 more source
Correction for Jang et al., Lipid raft proteomics identify endothelial myosin-9 (MYH9) as a regulator of low-density lipoprotein transcytosis and atherosclerosis. [PDF]
europepmc +1 more source
Docosahexaenoic Acid Controls Pulmonary Macrophage Lipid Raft Size and Inflammation. [PDF]
Pennington ER +14 more
europepmc +1 more source

