Results 231 to 240 of about 64,062 (299)

A Patching and Coding Lipid Raft-Localized Universal Imaging Platform. [PDF]

open access: yesChem Biomed Imaging
Zhong T   +10 more
europepmc   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui   +9 more
wiley   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

open access: yesAdvanced Science, Volume 13, Issue 24, 27 April 2026.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu   +9 more
wiley   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

open access: yesAdvanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi   +4 more
wiley   +1 more source

Aggregation‐Induced Resonance Energy Transfer in Polymer Dots to Boost Electrochemiluminescence Performance for Bioimaging of Glycan on Cells

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
This study pioneers an aggregation‐induced resonance energy transfer mechanism by synergistically integrating aggregation‐induced emission (AIE), resonance energy transfer (RET), and thermally activated delayed fluorescence (TADF) within co‐reactant conjugated polymers to develop self‐enhanced ECL emitters, which achieves an ECL efficiency up to 92.6 ...
Chao Wang   +6 more
wiley   +1 more source

A perspective: PLA2G4A as drug target for vascular inflammation in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract Anti‐amyloid therapies for Alzheimer's disease (AD) modestly slow cognitive decline but carry significant risk of amyloid‐related imaging abnormalities (ARIAs), brain swelling, and hemorrhage, particularly in apolipoprotein E ε4 carriers. Cerebral amyloid angiopathy (CAA) and vascular inflammation drive this vulnerability, highlighting the ...
Ambreen Kanwal   +12 more
wiley   +1 more source

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