A Patching and Coding Lipid Raft-Localized Universal Imaging Platform. [PDF]
Zhong T +10 more
europepmc +1 more source
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui +9 more
wiley +1 more source
Characterization and Fluctuations of an Ivermectin Binding Site at the Lipid Raft Interface of the N-Terminal Domain (NTD) of the Spike Protein of SARS-CoV-2 Variants. [PDF]
Lefebvre M +3 more
europepmc +1 more source
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
Expression of Concern for Interfering with Lipid Raft Association: A Mechanism to Control Influenza Virus Infection By Sambucus nigra [Iran J Pharm Res. 2017; 16 (3): e124953]. [PDF]
Ijpr EI.
europepmc +1 more source
Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi +4 more
wiley +1 more source
This study pioneers an aggregation‐induced resonance energy transfer mechanism by synergistically integrating aggregation‐induced emission (AIE), resonance energy transfer (RET), and thermally activated delayed fluorescence (TADF) within co‐reactant conjugated polymers to develop self‐enhanced ECL emitters, which achieves an ECL efficiency up to 92.6 ...
Chao Wang +6 more
wiley +1 more source
How Membrane Phospholipids Containing Long-Chain Polyunsaturated Fatty Acids and Their Oxidation Products Orchestrate Lipid Raft Dynamics to Control Inflammation. [PDF]
Virk R +5 more
europepmc +1 more source
A perspective: PLA2G4A as drug target for vascular inflammation in Alzheimer's disease
Abstract Anti‐amyloid therapies for Alzheimer's disease (AD) modestly slow cognitive decline but carry significant risk of amyloid‐related imaging abnormalities (ARIAs), brain swelling, and hemorrhage, particularly in apolipoprotein E ε4 carriers. Cerebral amyloid angiopathy (CAA) and vascular inflammation drive this vulnerability, highlighting the ...
Ambreen Kanwal +12 more
wiley +1 more source
Lipid raft disruption inhibits the activation of Transient Receptor Potential Vanilloid 1, but not TRP Melastatin 3 and the voltage-gated L-type calcium channels in sensory neurons. [PDF]
Payrits M +6 more
europepmc +1 more source

