Results 191 to 200 of about 34,012 (255)

Characterization and Fluctuations of an Ivermectin Binding Site at the Lipid Raft Interface of the N-Terminal Domain (NTD) of the Spike Protein of SARS-CoV-2 Variants. [PDF]

Viruses
Lefebvre M, Chahinian H, La Scola B, Fantini J.   +3 more
europepmc   +1 more source

Evaluating the Influence of Flaxseed Oil Against Docosahexaenoic Acid on Cancer Antigen CA15‐3, Biochemical and Histopathological Parameters of DMBA‐Induced Mammary Tumors Female Albino Wistar Rats

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Flaxseed oil and docosahexaenoic acid administered to female Wistar rats with DMBA‐induced breast cancer help increase the HDL cholesterol and significantly reduce the CA15‐3, AST, ALT, LDL, and creatinine levels of rats compared to the negative control group. They also exhibited a protective effect on organs from histopathological data.
Hilda Nji Aza, Fabrice Tonfack Djikeng, Achidi Aduni Ufuan, Ines Sorelle Fotsing, Stephane Zingue   +4 more
wiley   +1 more source

Expression of Concern for Interfering with Lipid Raft Association: A Mechanism to Control Influenza Virus Infection By Sambucus nigra [Iran J Pharm Res. 2017; 16 (3): e124953]. [PDF]

Iran J Pharm Res
Ijpr EI.
europepmc   +1 more source

Liensinine Ameliorating Oxidative Damage to Vascular Endothelium In Vitro via Upregulating eNOS and Nrf2/HO‐1 Signaling

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
The present studies of network pharmacology, molecular docking and molecular dynamics simulation indicated that liensinine might ameliorate oxidative damage to vascular endothelium (ODVE) by regulating the targets of Nrf2, which is encoded by the NFE2L2 gene. Then the in vitro study further showed that liensinine exhibited an obvious protection against
Feng Gao, Fengjiao Deng, Qiaowei Du, Tianya Xia, Yayi Deng, Shuang Liu, Bin Yu, Chenxiao Shan   +7 more
wiley   +1 more source

Artificial Sweeteners and Autoimmune Diseases: Insights From Integrative Bioinformatics and Mendelian Randomization

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study provides a novel molecular perspective on the role of AS in ADs development. We identified a positive association between artificially sweetened cereal intake and ADs risk and revealed multiple pathogenic mechanisms involving apoptosis, inflammatory signaling, immune activation, and gut microbiota dysbiosis.
Yupei Liu, Jizhen Huang, Xue Hu, Shan Tian, Jiao Li, Shiyun Tan, Weiguo Dong   +6 more
wiley   +1 more source

How Membrane Phospholipids Containing Long-Chain Polyunsaturated Fatty Acids and Their Oxidation Products Orchestrate Lipid Raft Dynamics to Control Inflammation. [PDF]

J Nutr
Virk R, Cook K, Cavazos A, Wassall SR, Gowdy KM, Shaikh SR.   +5 more
europepmc   +1 more source

Lipid raft disruption inhibits the activation of Transient Receptor Potential Vanilloid 1, but not TRP Melastatin 3 and the voltage-gated L-type calcium channels in sensory neurons. [PDF]

Front Cell Dev Biol
Payrits M, Zsidó BZ, Nehr-Majoros AK, Börzsei R, Helyes Z, Hetényi C, Szőke É.   +6 more
europepmc   +1 more source

Metabolic Reprogramming and Exosome Remodeling in an Ndufs4‐Deficient Model of Leigh Syndrome

iNew Medicine, Volume 2, Issue 2, June 2026.
Ndufs4 knockout drives exosomal remodeling, reprograms cellular metabolism, impairs neural stem cell self‐renewal and differentiation, and suppresses mTOR signaling, providing a conceptual framework for understanding Leigh syndrome pathogenesis and informing therapeutic development.
Yakun Liu, Zhi Yang, Zhencai Xing, Rongrong Zhao, Yixuan Zhou, Xue Yang, Jicheng Zhu, Shuo Chen, Yuhang Zhang, Mengxue Xu, Xiang Kong, Minqiong Sun, Zhenya Tan, Hong Zheng   +13 more
wiley   +1 more source

CD133 Shapes Extracellular Vesicle Cargo and Angiogenic Function in Basal‐Like Triple‐Negative Breast Cancer

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are central mediators of tumour‐stroma communication, yet the mechanisms governing their biogenesis and functional cargo remain poorly understood. Here, we identify CD133 (Prominin‐1), selectively expressed in basal‐like triple‐negative breast cancer (BL‐TNBC) cells, acts as a key organizer of EV production and ...
Mireia Gomez‐Duro, Ptissam Bergam, Sara Sanchez‐Redondo, Florent Dingli, Alix Zhou, Alain Joliot, Mengliang Ye, Marta Hergueta‐Redondo, Lucas Alves Tavares, Damarys Loew, Thierry Dubois, Lorena Martin‐Jaular, Hector Peinado, Graça Raposo, Gisela D'Angelo   +14 more
wiley   +1 more source

Neocarzilin Inhibits Cancer Cell Proliferation via BST-2 Degradation, Resulting in Lipid Raft-Trapped EGFR. [PDF]

JACS Au
Braun J, Hu Y, Jauch AT, Gronauer TF, Mergner J, Bach NC, Traube FR, Zahler S, Sieber SA.   +8 more
europepmc   +1 more source