Results 41 to 50 of about 1,129,041 (391)
The desmosome is a mesoscale lipid raft–like membrane domain
Desmogleins are cadherin family adhesion molecules essential for epidermal integrity. Previous studies have shown that desmogleins associate with lipid rafts, but the significance of this association was not clear.
Joshua D. Lewis+17 more
semanticscholar +1 more source
Host Lipid Rafts Play a Major Role in Binding and Endocytosis of Influenza A Virus
Influenza still remains one of the most challenging diseases, posing a significant threat to public health. Host lipid rafts play a critical role in influenza A virus (IAV) assembly and budding, however, their role in polyvalent IAV host binding and ...
Dileep Kumar Verma+2 more
doaj +1 more source
Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]
During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Andrew C. Gill+44 more
core +1 more source
Lipid raft is an important element for the cellular entry of some viruses, including coronavirus infectious bronchitis virus (IBV). However, the exact role of lipid rafts in the cellular membrane during the entry of IBV into host cells is still unknown ...
Huichen Guo+10 more
semanticscholar +1 more source
The role of lipid rafts in vesicle formation.
The formation of membrane vesicles is a common feature in all eukaryotes. Lipid rafts are the best-studied example of membrane domains for both eukaryotes and prokaryotes, and their existence also is suggested in Archaea membranes.
Karolina Sapoń+3 more
semanticscholar +1 more source
Pathogens, toxins, and lipid rafts [PDF]
The plasma membrane is not a uniform two-dimensional space but includes various types of specialized regions containing specific lipids and proteins. These include clathrin-coated pits and caveolae. The existence of other cholesterol- and glycosphingolipid-rich microdomains has also been proposed.
Fivaz, M., Abrami, L., van der Goot, F.
openaire +3 more sources
Cannabinoid receptors distribution in mouse cortical plasma membrane compartments
The type 1 and type 2 cannabinoid receptors (CB1 and CB2 receptors) are class A G protein-coupled receptors (GPCRs) that are activated by endogenous lipids called endocannabinoids to modulate neuronal excitability and synaptic transmission in neurons ...
Hajar Miranzadeh Mahabadi+3 more
doaj +1 more source
The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]
Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Cheng Zhu+2 more
core +2 more sources
Interaction of hyperlipidemia and reactive oxygen species: Insights from the lipid-raft platform
Reactive oxygen species (ROS) and oxidative stress are closely associated with the development of atherosclerosis, and the most important regulator of ROS production in endothelial cells is NADPH oxidase. Activation of NADPH oxidase requires the assembly
E. Amiya
semanticscholar +1 more source
Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. [PDF]
HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors.
Brichacek, Beda+15 more
core +3 more sources