Correction to: Regulation of TrkB receptor translocation to lipid rafts by adenosine A2A receptors and its functional implications for BDNF-induced regulation of synaptic plasticity. [PDF]
Assaife-Lopes N +4 more
europepmc +1 more source
Evidence for alterations in lipid profiles and biophysical properties of lipid rafts from spinal cord in sporadic amyotrophic lateral sclerosis. [PDF]
Díaz M +4 more
europepmc +1 more source
Defect in Migration of HSPCs in Nox-2 Deficient Mice Explained by Impaired Activation of Nlrp3 Inflammasome and Impaired Formation of Membrane Lipid Rafts. [PDF]
Bujko K +7 more
europepmc +1 more source
Low Density Lipoprotein Cholesterol Decreases the Expression of Adenosine A2A Receptor and Lipid Rafts-Protein Flotillin-1: Insights on Cardiovascular Risk of Hypercholesterolemia. [PDF]
Chaptal MC +13 more
europepmc +1 more source
Human growth factor-mediated signalling through lipid rafts regulates stem cell proliferation, development and survival of <i>Schistosoma mansoni</i>. [PDF]
Maharjan S +3 more
europepmc +1 more source
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Bacterial lipid rafts discovered
Nature Reviews Microbiology, 2010The identification and characterization of bacterial lipid rafts and their role in the signalling pathways that regulate biofilm formation inBacillus subtilis.
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Lipid rafts and signal transduction
Nature Reviews Molecular Cell Biology, 2000Signal transduction is initiated by complex protein-protein interactions between ligands, receptors and kinases, to name only a few. It is now becoming clear that lipid micro-environments on the cell surface -- known as lipid rafts -- also take part in this process. Lipid rafts containing a given set of proteins can change their size and composition in
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Lipid rafts are plasma membrane microdomains enriched in sphingolipids and cholesterol. These domains have been suggested to serve as platforms for various cellular events, such as signaling and membrane trafficking. However, little is known about the distribution and dynamics of lipids in these microdomains.
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Lipid Rafts in Exosome Biogenesis
Biochemistry (Moscow), 2020Exosomes (secreted extracellular vesicles formed in the intracellular vesicular transport system) play a crucial role in distant cell-cell communication. Exosomes transfer active forms of various biomolecules; the molecular composition of the exosomal cargo is a result of targeted selection and depends on the type of producer cells.
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Lipid microenvironments in the plasma membrane are known to influence many signal transduction pathways. Several of those pathways are critical for both the etiology and treatment of depression. Further, several signaling proteins are modified, covalently, by lipids, a process that alters their interface with the microenvironments mentioned above. This
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