SARS-CoV-2 entry and fusion are independent of ACE2 localization to lipid rafts. [PDF]
Bolland W +8 more
europepmc +1 more source
Dual‐Crosslinked Hydrogels With Enhanced Mechanical and Thermal Properties
An illustrative depiction of a dual‐crosslinked polymer network achieved with dynamic crosslinkers (blue) and covalent crosslinkers (red). ABSTRACT Creating artificial skin requires materials that can mimic the mechanical properties and structural integrity of natural skin.
Lilian Boton +2 more
wiley +1 more source
Exploring the Dynamic Changes of Brain Lipids, Lipid Rafts, and Lipid Droplets in Aging and Alzheimer's Disease. [PDF]
Cerasuolo M +5 more
europepmc +1 more source
Increases in sphingomyelin in response to TDP‐43 pathology in the disease‐affected motor cortex of amyotrophic lateral sclerosis (ALS) brain. Abstract Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease characterized by the degeneration of motor neurons and the presence of TAR DNA‐binding protein 43 (TDP‐43 ...
Finula I. Isik +4 more
wiley +1 more source
Cholesterol and Lipid Rafts in the Biogenesis of Amyloid-β Protein and Alzheimer's Disease. [PDF]
Pantelopulos GA, Abraham CB, Straub JE.
europepmc +1 more source
SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley +1 more source
Iron-associated lipid peroxidation in Alzheimer's disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice. [PDF]
Thorwald MA +14 more
europepmc +1 more source
ACSL4-mediated lipid rafts prevent membrane rupture and inhibit immunogenic cell death in melanoma. [PDF]
Zhao X +6 more
europepmc +1 more source
This study presents the highly efficient heterologous production of the human blood group glycosyltransferases GTA/R176A and GTB, along with their comprehensive biochemical and kinetic characterization. Tailored enzyme cascades, involving the bacterial fucosyltransferase FutC and GTA or GTB, generate milligram quantities of various blood group ABH ...
Katja Pöstges +8 more
wiley +1 more source
Enhancing PD-1 blockade in NSCLC: Reprogramming tumor immune microenvironment with albumin-bound statins targeting lipid rafts and mitochondrial respiration. [PDF]
Chen N +8 more
europepmc +1 more source

