ChemSystemsChem, Volume 8, Issue 5, September 2026.DNA origami nanostructures functionalized with lipophilic anchors of distinct hydrophobicity reveal synergistic effects on membrane binding and phase‐specific localization. Weak anchors, although insufficient for binding alone, enhance membrane association and govern selective phase partitioning when combined with strong anchors, establishing multi ...
Subhasini Singh, Henri G. Franquelim
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GDF15 promotes the resistance of epithelial ovarian cancer cells to gemcitabine via DHCR24-mediated cholesterol metabolism to elevate ABCB1 and ABCC1 levels in lipid rafts. [PDF]
Am J Cancer ResGuo L, He Y, Xin H.
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Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.ABSTRACT With the recent introduction of the European Union's Packaging and Packaging Waste Regulation (PPWR) in February 2025, reusable plastic packaging schemes have gained increasing attention as a more circular and sustainable alternative to single‐use plastics (SUPs).
Ronan Farrell +3 more
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Alpha-hemolysin promotes internalization of Staphylococcus aureus into human lung epithelial cells via caveolin-1- and cholesterol-rich lipid rafts. [PDF]
Cell Mol Life SciGoldmann O +5 more
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Biogenesis of TNF‐α‐insights into proteostasis and inflammation
The FEBS Journal, Volume 293, Issue 18, Page 5645-5663, September 2026.TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar +3 more
wiley +1 more source
Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response
The FEBS Journal, Volume 293, Issue 18, Page 5481-5513, September 2026.Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril +2 more
wiley +1 more source
Modelling lipid rafts formation through chemo-mechanical interplay triggered by receptor-ligand binding. [PDF]
Biomech Model MechanobiolBernard C +4 more
europepmc +1 more source
Cinobufagin disrupts the stability of lipid rafts by inhibiting the expression of caveolin-1 to promote non-small cell lung cancer cell apoptosis. [PDF]
Arch Med SciXu Z +6 more
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Domains and Rafts in Lipid Membranes
Angewandte Chemie - International Edition, 2003Abstract“It takes a membrane to make sense out of disorder in biology. You have to be able to catch energy and hold it, storing precisely the needed amount and releasing it in measured shares”. So wrote Lewis Thomas in The Lives of Cells. Domains and rafts are shown in the present Review to play an important role in this amazing behavior of lipid ...
Wolfgang H Binder
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Lipid rafts and signal transduction
Nature Reviews Molecular Cell Biology, 2000Signal transduction is initiated by complex protein-protein interactions between ligands, receptors and kinases, to name only a few. It is now becoming clear that lipid micro-environments on the cell surface -- known as lipid rafts -- also take part in this process. Lipid rafts containing a given set of proteins can change their size and composition in
Kai Simons, D Toomre
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