Results 191 to 200 of about 6,052,075 (348)

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Bioactive lipid signaling and lipidomics in macrophage polarization: Impact on inflammation and immune regulation. [PDF]

Front Immunol
Rodríguez JP, Casas J, Balboa MA, Balsinde J.   +3 more
europepmc   +1 more source

Lipid Raft Heterogeneity in Human Peripheral Blood T Lymphoblasts: A Mechanism for Regulating the Initiation of TCR Signal Transduction [PDF]

, 2002
Andrew E. Schade, Alan D. Levine
openalex   +1 more source

A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation

Advanced Functional Materials, EarlyView.
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou, Supun Ranaweera, Xiangke Li, Ruirui Qiao, Yue Hui, Chun‐Xia Zhao   +5 more
wiley   +1 more source

Nanoparticles and Their Applications in Lipid Signaling. [PDF]

Methods Mol Biol
Ashin ZF, Yacoub AS, Saady M, Thompson SE, Awad K, Aswath P, Brotto M, Varanasi V.   +7 more
europepmc   +1 more source

Quantifying single cell lipid signaling kinetics after photo-stimulation

, 2023
Gonzales DT, Schuhmacher M, Lennartz HM, Iglesias-Artola JM, Kuhn SM, Barahtjan P, Zechner C, Nadler A.   +7 more
europepmc   +1 more source

Mitochondrial damage & lipid signaling in traumatic brain injury. [PDF]

Exp Neurol, 2020
Lamade AM, Anthonymuthu TS, Hier ZE, Gao Y, Kagan VE, Bayır H.   +5 more
europepmc   +1 more source

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

Advanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri, Xinan Huang, Emanuel Lörtscher, Cora‐Ann Schoenenberger, Cornelia G. Palivan   +4 more
wiley   +1 more source

Lipid signaling: facets of a versatile cell communication strategy in health and disease. [PDF]

Pflugers Arch
Gulbins E, Pfeilschifter J.
europepmc   +1 more source

Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program

Proceedings of the National Academy of Sciences of the United States of America, 2016
Cody Kime, M. Sakaki-Yumoto, L. Goodrich, Y. Hayashi, Salma Sami, R. Derynck, M. Asahi, B. Panning, S. Yamanaka, K. Tomoda   +9 more
semanticscholar   +1 more source