Results 211 to 220 of about 564,255 (265)
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A Convergent Approach to the Synthesis of Lipid A
Clinical Infectious Diseases, 1984To accomplish the synthesis of compounds having the essential structural features of bacterial lipid A, one must assemble a glucosamine disaccharide bearing five to seven substituents (fatty acyl groups, phosphate ester groups) at specific positions. In the convergent synthesis described, a protected glycoside prepared from D-glucosamine hydrochloride ...
L, Anderson, M A, Nashed
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Modification of Plant Lipid Synthesis
Science, 1995Genetic engineering of new storage oils and fats has produced oil crop plants with fatty acid compositions unattainable by plant breeding alone. The combination of classical breeding methods with molecular techniques provides new ways for designing oils for food and nonfood uses.
R, Töpfer, N, Martini, J, Schell
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Triclosan targets lipid synthesis
Nature, 1998Triclosan is a broad-spectrum antibacterial and antifungal agent1,2, which acts by previously undetermined mechanisms, that is used in products such as antiseptic soaps, toothpastes, fabrics and plastics. Here we show that triclosan blocks lipid synthesis in Escherichia coli, and that mutations in, or overexpression of, the gene fabI (which encodes ...
L M, McMurry, M, Oethinger, S B, Levy
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2009
In this review, an overview is given for the synthesis of lipidated peptides such as those belonging to the Rab, Ras, eNOS, and hedgehog proteins. The different approaches for the synthesis of specific lipidated peptides (palmitoylated, prenylated, and myristoylated) are discussed with special emphasis on solid-phase synthesis methods, because these ...
Gerauer, M. +3 more
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In this review, an overview is given for the synthesis of lipidated peptides such as those belonging to the Rab, Ras, eNOS, and hedgehog proteins. The different approaches for the synthesis of specific lipidated peptides (palmitoylated, prenylated, and myristoylated) are discussed with special emphasis on solid-phase synthesis methods, because these ...
Gerauer, M. +3 more
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Lipid synthesis by perfused lung
Lipids, 1976AbstractAn isolated lung ventilated with pulses of negative pressure and perfused through the pulmonary vasculature was utilized for the study of 3‐sn‐phosphatidylcholine synthesis. The perfusion fluid consisted of a Krebs‐Ringer phosphate buffer with 6% bovine serum albumin, pH 7.4, and the appropriate substrate.
E G, Tombropoulos, J G, Hadley
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The Total Synthesis of Lipid I
Journal of the American Chemical Society, 2001A total synthesis of lipid I (4), a membrane-associated intermediate in the bacterial cell wall (peptidoglycan) biosynthesis pathway, is reported. This highly convergent synthesis will enable further studies on bacterial resistance mechanisms and may provide insight toward the development of new chemotherapeutic agents with novel modes of action.
M S, VanNieuwenhze +4 more
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Efficiency of lipid synthesis by yeasts
Biotechnology and Bioengineering, 1983AbstractThe efficiency of lipid synthesis by ethanol‐grown yeasts is characterized using the coefficient of the lipid energetic yield (η1). This coefficient is defined as the fraction of energy in an organic substrate that is converted to lipids. The advantages of η1 compared with the “fat coefficient” (Fs) as well as the biomass energetic yield (η ...
V K, Eroshin, N I, Krylova
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Lipid synthesis in the bovine lens
Current Eye Research, 1987Lipid synthesis was investigated in bovine lens in organ culture for 9 hours using 14C acetate as a precursor. The greatest incorporation occurred in phospholipid fraction with phosphatidyl choline being the major phospholipid labeled. Considerable activity was incorporated in the free fatty acid fraction, cholesterol and cholesterol intermediates.
B, Albers-Jackson, A, Nga Do
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Drugs affecting lipid synthesis
Journal of the American Oil Chemists' Society, 1964AbstractThe apparent direct casual relationship of elevated blood lipids to the pathogenesis of atherosclerosis has resulted in many lines of investigation directed toward the control of lipids, particularly cholesterol, in blood and tissues. Much of this work during the past decade has been concerned with the regulation of endogenous synthesis of ...
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British Journal of Dermatology, 1972
Summary.— Rat dorsal skin was fractionated by means of an electrokeratotome into epidermis and dermis containing the sebaceous glands. These fractions were separately cultured in the presence of 32P-orthophosphate, 14C-acetate, 14-glycerol and 14C-mevalonate, and the radioactivity incorporated into different classes of lipids was measured.
C, Prottey, P J, Hartop, T F, Ferguson
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Summary.— Rat dorsal skin was fractionated by means of an electrokeratotome into epidermis and dermis containing the sebaceous glands. These fractions were separately cultured in the presence of 32P-orthophosphate, 14C-acetate, 14-glycerol and 14C-mevalonate, and the radioactivity incorporated into different classes of lipids was measured.
C, Prottey, P J, Hartop, T F, Ferguson
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