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The role of lipids in heme synthesis
Lipids, 1969AbstractThe effect of lipids on protoheme ferrolyase, which combines ferrous iron with protoporphyrin, was investigated. The enzyme extracted with 1% Na cholate from acetone‐dried powder of chicken erythrocyte stroma showed high enzymic activity, while that extracted with 0.4 M KCl showed little activity.
Y, Yoneyama +3 more
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Synthesis of lipidic tamoxifen
Tetrahedron Letters, 2000Abstract We describe a general method for elaboration of the ethyl sidechain of tamoxifen and its primary 4-hydroxy metabolite. Novel lipidic tamoxifen and a functionalized B-ring analog were synthesized from a common stilbene oxide intermediate for potential liposomal applications including estrogen receptor targeting.
Matthew R Lashley, Michael H Nantz
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Chemoenzymatic Synthesis of Lipidated
2000This review highlights the use of enzymatic protecting group techniques in the synthesis of lipidated peptides. Lipidated proteins play key roles in signal transduction processes. Moreover, structurally well-defined peptides containing the characteristic linkage region of the peptide backbone with the lipid can provide valuable tools for the study of ...
Dieter Kadereit, Herbert Waldmann
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1990
The high interest of the studies of plant lipids is justified by their various roles in plant growth and development: i/ lipids play important structural roles since they are major constituents of cell membranes ; ii/ lipids can control, in some extent, the activity of membrane-bound enzymes ; iii/ various membrane proteins are esterified at their N ...
Jean-Claude Kader, Pascal Laurent
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The high interest of the studies of plant lipids is justified by their various roles in plant growth and development: i/ lipids play important structural roles since they are major constituents of cell membranes ; ii/ lipids can control, in some extent, the activity of membrane-bound enzymes ; iii/ various membrane proteins are esterified at their N ...
Jean-Claude Kader, Pascal Laurent
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Design, synthesis and lipid-lowering activities of penipyridone derivatives
Bioorganic and Medicinal Chemistry, 2021Jiejie Hao, Tianjiao Zhu
exaly