Results 71 to 80 of about 611,612 (297)

Tuning ubiquinone position in biomimetic monolayer membranes [PDF]

open access: yes, 2017
Artificial lipid bilayers have been extensively studied as models that mimic natural membranes (biomimetic membranes). Several attempts of biomimetic membranes inserting ubiquinone (UQ) have been performed to enlighten which the position of UQ in the ...
Guaus Guerrero, Ester   +2 more
core   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Hepatocellular triglyceride synthesis and transfer to lipid droplets and nascent very low density lipoproteins.

open access: yesJournal of Lipid Research, 1990
The transfer of triglyceride from sites of synthesis in the endoplasmic reticulum to cytoplasmic lipid droplets and nascent VLDL (very low density lipoproteins) in rat liver in vivo has been examined with [3H]glycerol, cell fractionation, and electron ...
F F Chao, D L Stiers, J A Ontko
doaj   +1 more source

Bridge-Like Lipid Transfer Proteins (BLTPs) in : From Genetics to Structures and Functions

open access: yesContact, 2023
In eukaryotic cells, lipid transfer can occur at membrane contact sites (MCS) to facilitate the exchange of various lipids between two adjacent cellular organelle membranes. Lipid transfer proteins (LTPs), including shuttle LTP or bridge-like LTP (BLTP),
Taruna Pandey   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The effect of polar lipids on tear film dynamics [PDF]

open access: yes, 2009
In this paper we present a mathematical model describing the effect of polar lipids on the evolution of a precorneal tear film, with the aim of explaining the interesting experimentally observed phenomenon that the tear film continues to move upwards ...
A. Heryudono   +28 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Study on Molecular Thermal Energy Transfer in a Lipid Bilayer

open access: yesJournal of Thermal Science and Technology, 2008
Recently, lipid bilayers attract a great deal of interest as a material with nanoscale structure. Various devices utilizing lipid bilayers, which include some kinds of sensors and molecular sorting devices, have been proposed.
Takeo NAKANO, Taku OHARA, Gota KIKUGAWA
doaj   +1 more source

Properties of the mechanosensitive channel MscS pore revealed by tryptophan scanning mutagenesis [PDF]

open access: yes, 2015
Funding This work was supported by a Wellcome Trust Programme grant [092552/A/10/Z awarded to I.R.B., S.M., J. H. Naismith (University of St Andrews, St Andrews, U.K.), and S. J. Conway (University of Oxford, Oxford, U.K.)] (T.R.
Akiko Rasmussen   +12 more
core   +4 more sources

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