Results 211 to 220 of about 32,392 (245)
Lipidomics unveils the complexity of the lipidome in metabolic diseases [PDF]
Clinical and Translational Medicine, 2018 AbstractDysregulation of lipid metabolism is responsible for pathologies of human diseases including metabolic diseases. Recent advances in lipidomics analysis allow for the targeted and untargeted identification of lipid species and for their quantification in normal and diseased conditions.
Todd A Lydic, Young-Hwa Goo
exaly +4 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Profiling the Mammalian Lipidome by Quantitative Shotgun Lipidomics
2023The emerging field of lipidomics presents the systems biology approach to identify and quantify the full lipid repertoire of cells, tissues, and organisms. The importance of the lipidome is demonstrated by a number of biological studies on dysregulation of lipid metabolism in human diseases such as cancer, diabetes, and neurodegenerative diseases ...
Mads Møller, Foged +2 more
openaire +2 more sources
Current Opinion in Clinical Nutrition and Metabolic Care, 2012
Lipidomics characterizes the composition of intact lipid molecular species in biological systems and the field has been driven by some spectacular advances in mass spectrometry instrumentation and applications. This review will highlight these advances and outline their recent application to address clinical issues.This review first identifies recent ...
openaire +3 more sources
Lipidomics characterizes the composition of intact lipid molecular species in biological systems and the field has been driven by some spectacular advances in mass spectrometry instrumentation and applications. This review will highlight these advances and outline their recent application to address clinical issues.This review first identifies recent ...
openaire +3 more sources
Prostaglandins & Other Lipid Mediators, 2005
Lipidomics the systematic decoding of lipid-based information in biosystems is comprised of identification and profiling of lipids and lipid-derived mediators. As practiced today, lipidomics can be subdivided into architecture/membrane-lipidomics and mediator-lipidomics. The mapping of structural components and their relation to cell activation as well
openaire +2 more sources
Lipidomics the systematic decoding of lipid-based information in biosystems is comprised of identification and profiling of lipids and lipid-derived mediators. As practiced today, lipidomics can be subdivided into architecture/membrane-lipidomics and mediator-lipidomics. The mapping of structural components and their relation to cell activation as well
openaire +2 more sources
2007
Lipids are recognized as key participants in the regulation and control of cellular function, having important roles in signal transduction processes. The diversity in lipid chemical structure presents a challenge for establishing practical methods to generate and manage high volumes of complex data that translate into a snapshot of cellular lipid ...
Eoin, Fahy +8 more
openaire +2 more sources
Lipids are recognized as key participants in the regulation and control of cellular function, having important roles in signal transduction processes. The diversity in lipid chemical structure presents a challenge for establishing practical methods to generate and manage high volumes of complex data that translate into a snapshot of cellular lipid ...
Eoin, Fahy +8 more
openaire +2 more sources
Quantitative Profiling of Lysosomal Lipidome by Shotgun Lipidomics
2017Recent studies have illuminated novel roles of lysosomes that go far beyond simple catabolism and function in the coordination of cellular metabolism and signaling. Promising therapeutic strategies emerge from knowledge in the molecular mechanisms and physiological roles of lipid metabolism in lysosomes.
Mesut Bilgin +3 more
openaire +2 more sources
Lipidomics of Alzheimer’s Disease
Bioanalysis, 2014Alzheimer's disease (AD) is a progressive brain disease that leads to an irreversible loss of neurons and cognition. It is the most common cause of dementia and can be considered as a major public health problem. At the histological level, AD is characterized by senile plaques and neurofibrillary tangles.
Touboul, David, Gaudin, Mathieu
openaire +3 more sources
Analysis of the Mammalian Lipidome by DMS Shotgun Lipidomics
Shotgun Lipidomics is a robust methodology for the characterization of the lipidome of complex biological samples. This assay is among the most quantitative lipidomics methods and is capable of surveying a wide breadth of lipid subclasses, both neutral and polar.Baolong, Su, Kevin J, Williams
openaire +2 more sources
Single-cell lipidomics reveals the organizing principle of cell fate decision
Nature Reviews Molecular Cell Biology, 2023Laura Capolupo
exaly
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2003
Michel, Lagarde +4 more
openaire +2 more sources
Michel, Lagarde +4 more
openaire +2 more sources