Results 201 to 210 of about 42,745 (295)
Dapagliflozin Alters Plasma Metabolome in Patients With Type 1 Diabetes During Ketosis
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Use of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 1 diabetes (T1D) is limited by increased risk of ketoacidosis. We aimed to determine metabolic pathways affected by SGLT2i treatment in adults with T1D during ketosis induced by insulin withdrawal.
Rosa Yang +6 more
wiley +1 more source
The FEBS Journal, EarlyView.Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
Integrative computational analysis of public fecal lipidomics and transcriptomics datasets suggests a candidate association between the COX-2 pathway and CE(20:4) in colorectal adenoma-carcinoma progression. [PDF]
PLoS OneTang B, Chen Y, Yang X, Gong H.
europepmc +1 more source
The FEBS Journal, EarlyView.Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki +7 more
wiley +1 more source
Putative Adverse Outcome Pathway in Kashin-Beck Disease Suggested by Lipidomics and Network Toxicology - Xi'an City, Shaanxi Province, China, 2023-2025. [PDF]
China CDC WklyCui L +17 more
europepmc +1 more source
Circadian rhythms of metabolite abundance in Drosophila are largely driven by time of feeding
The FEBS Journal, EarlyView.Circadian clocks exist in the brain and peripheral tissues such as the Drosophila fat body. Single‐nuclei transcriptomics reveal that the fat body clock generates time‐of‐day differences in metabolic gene transcription, which may also be indirectly controlled by brain clocks.
Sumit Saurabh +7 more
wiley +1 more source
A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet
The FEBS Journal, EarlyView.C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr +4 more
wiley +1 more source
A guide to laser microdissection‐based proteomics
The FEBS Journal, EarlyView.This review takes researchers through the full laser microdissection proteomics workflow—from tissue preparation and image analysis to sample processing and mass spectrometry—offering practical solutions to common challenges at each step. Real‐world examples from across the field illustrate how the technology is being applied to disease tissue, making ...
Cheng Shen +3 more
wiley +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic +3 more
wiley +1 more source
Urinary Lipid Production Profile of Patients With Food Allergy
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 256-259, March 2025.
Sakura Masuko +10 more
wiley +1 more source