Results 71 to 80 of about 36,737 (293)

Lipidomics raw data for KirBac [PDF]

, 2021
Raw data for the lipidomics analysis of ...
Di Wu (5598773)
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

On Mass Ambiguities in Shotgun Lipidomics [PDF]

, 2016
Mass-spectrometry based lipidomics aims to identify as many lipid species as possible from complex biological samples. Due to the large combinatorial search-space unambiguous identification of lipid species is far from trivial.
S. Kempa, C. Bielow, M. Orioli, G. Mastrobuoni   +3 more
core  

Lipidomics raw data for SthK [PDF]

, 2022
Raw MS data for lipidomics analysis of SthK ...
Crina M. Nimigean (9905171), Di Wu (5598773), Philipp A. M. Schmidpeter (453850), Haiping Tang (394380), Carol V. Robinson (8273049), Jan Rheinberger (9905169)   +5 more
core   +1 more source

Evaluating Software Tools for Lipid Identification from Ion Mobility Spectrometry–Mass Spectrometry Lipidomics Data

Molecules, 2023
The unambiguous identification of lipids is a critical component of lipidomics studies and greatly impacts the interpretation and significance of analyses as well as the ultimate biological understandings derived from measurements.
Dylan H. Ross, Jian Guo, Aivett Bilbao, Tao Huan, Richard D. Smith, Xueyun Zheng   +5 more
doaj   +1 more source

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

Advanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco, Roberto Baretta, Andrea Di Fonzo, Andrea Armirotti, Stefano Cinti, Mara Mirasoli, Marco Frasconi, Claudia Corbo   +7 more
wiley   +1 more source

BioPAN: a web-based tool to explore mammalian lipidome metabolic pathways on LIPID MAPS [version 1; peer review: 2 approved]

F1000Research, 2021
Lipidomics increasingly describes the quantitation using mass spectrometry of all lipids present in a biological sample.  As the power of lipidomics protocols increase, thousands of lipid molecular species from multiple categories can now be profiled in ...
Caroline Gaud, Bebiana C. Sousa, An Nguyen, Maria Fedorova, Zhixu Ni, Valerie B. O’Donnell, Michael J.O. Wakelam, Simon Andrews, Andrea F. Lopez-Clavijo   +8 more
doaj   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

Advanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang, Tan Wei, Jiahang Wu, Chuixu Lin, Dongbo Zhu, Yanhui Li, Shuting Shi, Shishun Huang, Leiming Jiang, Hongzhi Wang, Meiqi Song, Pengfei Gao, Xu Wu, Mingjian Fan, Chaofeng Wei, Qian Wang, Lihui Qu, Zhigang Wang   +17 more
wiley   +1 more source

BioPAN: a web-based tool to explore mammalian lipidome metabolic pathways on LIPID MAPS [version 2; peer review: 3 approved]

F1000Research, 2021
Lipidomics increasingly describes the quantification using mass spectrometry of all lipids present in a biological sample.  As the power of lipidomics protocols increase, thousands of lipid molecular species from multiple categories can now be profiled ...
Caroline Gaud, Bebiana C. Sousa, An Nguyen, Maria Fedorova, Zhixu Ni, Valerie B. O’Donnell, Michael J.O. Wakelam, Simon Andrews, Andrea F. Lopez-Clavijo   +8 more
doaj   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

Advanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha, Ashwani Kumar Gupta, Nate Schmidt, Richard M. Green, John G. Purdy, Jason A. Wertheim   +5 more
wiley   +1 more source