Lipocalin-1 Expression as a Prognosticator Marker of Survival in Breast Cancer Patients [PDF]
<b><i>Purpose:</i></b> LCN1 (lipocalin-1), a gene that encodes tear lipocalin (or von Ebner’s gland protein), is mainly expressed in secretory glands and tissues, such as the lachrymal and lingual gland, and nasal, mammary, and tracheobronchial mucosae.
Xueyan Zhang +4 more
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Background:Laparoscopic partial nephrectomy, which minimizes renal function loss due to its nephron sparing nature, has become a standard technique among many experienced centers worldwide for surgical treatment of localized kidney tumors.
Meltem Savran Karadeniz +7 more
doaj +2 more sources
Neutrophil Gelatinase-Associated Lipocalin induces the expression of heme oxygenase-1 and superoxide dismutase 1, 2 [PDF]
Lipocalin-2 (Lcn2, NGAL) is a member of the lipocalin super family with diverse function such as the induction of apoptosis, the suppression of bacterial growth, and modulation of inflammatory response. Much interest has recently been focused on the physiological/pathological role of the lipocalin-2 that is considered to be a novel protective factor ...
Parisa, Bahmani +8 more
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Kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin as prognostic markers in idiopathic membranous nephropathy [PDF]
Background Urinary excretion of alpha-1-microglobulin and beta-2-microglobulin reflects tubular damage and predicts outcome in patients with idiopathic membranous nephropathy with reasonable accuracy. Urinary kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin are novel biomarkers of tubular ...
Maas, R.J.H. +7 more
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Despite a number of studies on biomarkers in chronic obstructive pulmonary disease (COPD), only a few disease-related markers have been identified, yet we still have no satisfactory markers specific to innate immune system and neutrophil activation, which is essential in airway inflammation in COPD.
Wang,Xiao-ru +12 more
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Diverse DTPA‐chelated lanthanides with relevance for nuclear medicine bound to an engineered lipocalin reveal conserved ligand geometry [PDF]
Structural and binding studies of the engineered lipocalin CL31d towards the chelate complexes of 11 different lanthanide and main‐group metal(III) ions, whose radioisotopes are useful for nuclear medicine, with a functionalized DTPA revealed a surprisingly broad tolerance towards varying ionic radii, thus enabling flexible radionuclide‐targeting ...
Alina Mirwald +2 more
wiley +2 more sources
The Role of Nitric Oxide, Lipocalin-2, and Proinflammatory Cytokines on Proteinuria and Insulin Resistance in Type 2 Diabetes Mellitus Subgroups [PDF]
Chung Hyun Nahm,1 Moon Hee Lee,2 Noriyoshi Fujii,3 Tatsuyoshi Fujii,4 Jong Weon Choi1 1Department of Laboratory Medicine, College of Medicine, Inha University, Incheon, Republic of Korea; 2Department of Internal Medicine, College of Medicine, Inha ...
Nahm CH +4 more
doaj +1 more source
Effects of Acute Low‐ and Moderate‐Dose Alcohol on Chronic Disease‐Related Biomarkers in Healthy Light and Heavy Drinkers [PDF]
This randomized, placebo‐controlled trial compared the effects of low‐ and moderate‐dose alcohol on biomarkers related to chronic disease in light and heavy drinkers. We identified novel acute alcohol effects as well as between‐group differences suggestive of pathophysiological processes by which alcohol use may promote chronic disease.
Mollie A. Monnig +2 more
wiley +2 more sources
The potential clinical significance of immunomodulation of immune and inflammatory responses involving selected adipokines in patients with ovarian cancer – preliminary studies [PDF]
Ovarian cancer (OC) is a major clinical problem in gynaecological oncology, characterised by difficulties in early diagnosis, which contributes to the high mortality rate from OC.
Sebastian Stępień +4 more
doaj +2 more sources
Antisense Down-regulation of Lipocalin-interacting Membrane Receptor Expression Inhibits Cellular Internalization of Lipocalin-1 in Human NT2 Cells [PDF]
There is increasing experimental evidence demonstrating that many lipocalins bind to specific cell surface receptors. However, whereas the binding of lipocalins to their lipophilic ligands has now been characterized in much detail, there is a lack of knowledge about the nature of lipocalin receptors, the physiological role of receptor binding, and the ...
Petra, Wojnar +2 more
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