Results 101 to 110 of about 22,237 (207)

Steatohepatitis Associated with Limb Lipodystrophy

, 1989
Two patients who presented with steatohepatitis had acquired partial lipodystrophy. This association has not previously been well documented. A common pathophysiological mechanism in lipodystrophy, obesity-associated nonalcoholic steatohepatitis, and ...
Powell, Elizabeth E., Powell, EE, Searle, J, Mortimer, R, Searle, Jeffrey, Mortimer, Robin   +5 more
core   +1 more source

Surplus fatty acid synthesis increases oxidative stress in adipocytes and induces lipodystrophy

Nature Communications
Adipocytes are the primary sites for fatty acid storage, but the synthesis rate of fatty acids is very low. The physiological significance of this phenomenon remains unclear.
Li Weng, Wen-Shuai Tang, Xu Wang, Yingyun Gong, Changqin Liu, Ni-Na Hong, Ying Tao, Kuang-Zheng Li, Shu-Ning Liu, Wanzi Jiang, Ying Li, Ke Yao, Li Chen, He Huang, Yu-Zheng Zhao, Ze-Ping Hu, Youli Lu, Haobin Ye, Xingrong Du, Hongwen Zhou, Peng Li, Tong-Jin Zhao   +21 more
doaj   +1 more source

Body Image perception in HIV-infected women with lipodystrophy syndrome

, 2001
To identify clinical and personal factors associated with increased depression and decreased quality of life with a focus on the contribution of adverse drug effects and, in particular, the morphologic and metabolic complications associated with ...
Orlando G., GUARALDI, Giovanni, Covezzi R., Amorico G., Murri R., Orlandi E., ESPOSITO, Roberto, Bedini A.   +7 more
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Evaluation of Coronavirus Disease 2019-Related Morbidity and Mortality in Lipodystrophy Patients During the Pandemic Period

Objective: Coronavirus Disease 2019's (COVID-19) impact on rare disease populations such as lipodystrophy syndromes is unknown. We assessed COVID-19 infection outcomes in lipodystrophy syndromes and aimed to investigate the effect of restricted access to
Bahri Evren, Onay, Hueseyin, ELLİDOKUZ, HÜLYA, Simsir, Ilgin Yildirim, Selimoğlu, İsmail, Semiz, GÖKÇEN, Gen, Ramazan, Gökçen Güngör Semiz, Yılmaz, Müge, Hülya Ellidokuz, Hüseyin Onay, Müge Yılmaz, Ramazan Gen, Şimşir, Ilgın Yıldırım, Yilmaz, Muege, Onay, Hüseyin, Demir, Tevfik, Tevfik Demir, Semiz, Gokcen Gungor, Ellidokuz, Huelya, EVREN, BAHRİ, Ilgın Yıldırım Şimşir, İsmail Selimoğlu   +22 more
core   +1 more source

A real-world pharmacovigilance assessment and literature review of lymphoma development in lipodystrophy

Frontiers in Endocrinology
IntroductionMetreleptin is a form of leptin replacement therapy used with diet and lifestyle modifications to treat the metabolic complications of leptin deficiency in lipodystrophy, a rare disease characterized by adipose tissue deficiency.
Rebecca J. Brown, David Araujo-Vilar, Kelly J. Walkovich, Alexandru Barbarosie, David A. Magee, Baris Akinci, Elif A. Oral   +6 more
doaj   +1 more source

HIV-associated lipodystrophy: a review from a Brazilian perspective

, 2014
Marcelle D Alves,1 Carlos Brites,2 Eduardo Sprinz1,31Infectious Disease Department, Hospital de Clínicas de Porto Alegre, Rio Grande do Sul, Brazil; 2School of Medicine, Federal University of Bahia, Salvador, Brazil; 3School of Medicine, Federal ...
Alves MD, Sprinz E, Brites C
core  

A rapid action plan to improve diagnosis and management of lipodystrophy syndromes

Frontiers in Endocrinology
IntroductionLipodystrophy syndromes are rare diseases that can present with a broad range of symptoms. Delays in diagnosis are common, which in turn, may predispose to the development of severe metabolic complications and end-organ damage.
Lindsay T. Fourman, Josivan Gomes Lima, Vinaya Simha, Marco Cappa, Saif Alyaarubi, Renan Montenegro, Baris Akinci, Baris Akinci, Ferruccio Santini   +8 more
doaj   +1 more source

Estimating the prevalence of generalized and partial lipodystrophy: findings and challenges

, 2017
Elaine Chiquette,1 Elif A Oral,2 Abhimanyu Garg,3 David Araújo-Vilar,4 Praveen Dhankhar5 1Aegerion Pharmaceuticals, Cambridge, MA, USA; 2Brehm Center for Diabetes Research and Metabolism, Endocrinology and Diabetes Division, Department of Internal
Oral EA, Dhankhar P, Garg A, Araújo-Vilar D, Chiquette E   +4 more
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Lipodystrophy [PDF]

Proceedings of the Royal Society of Medicine, 1933
openaire   +2 more sources

New advances in the treatment of generalized lipodystrophy: role of metreleptin

, 2015
Alexander J Rodriguez,1 Claudio A Mastronardi,2 Gilberto J Paz-Filho2 1Department of Medicine, Monash Medical Centre, Clayton, VIC, 2Department of Genome Sciences, The John Curtin School of Medical Research, The Australian National University, Canberra ...
Paz-Filho GJ, Rodriguez AJ, Mastronardi CA   +2 more
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