Results 81 to 90 of about 22,237 (207)
Metabolic Syndrome: From Mechanisms to Therapeutic Interventions
A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
wiley +1 more source
Voice Quality in Individuals With Acquired Immunodeficiency Syndrome
ABSTRACT Background Speech and voice disorders are frequently observed in individuals with acquired immunodeficiency syndrome (AIDS). However, the literature lacks detailed descriptions of how perceptual and acoustic characteristics manifest in the voice quality profiles of this population.
Vanessa Medina +4 more
wiley +1 more source
Generalized Lipodystrophy [PDF]
M, SEIP, O, TRYGSTAD
openaire +5 more sources
Hutchinson‐Gilford progeria syndrome (HGPS) is a premature aging disorder caused by a mutation in LMNA that produces the toxic progerin protein. In this study, an adenine base editor delivered via AAV9 achieved partial gene correction in HGPS mice when given at two weeks of age, partially rescuing bone structural and gene expression parameters and ...
Wayne A. Cabral +17 more
wiley +1 more source
Abstract Objectives Research suggests that some adults with visible differences may experience challenges related to romantic relationships, sex and physical intimacy. Loving ACTion is a self‐guided Acceptance and Commitment Therapy (ACT)‐based intervention delivered as an audio podcast series, co‐produced with adults with visible differences and ...
Maia Thornton +6 more
wiley +1 more source
Abstract A common misconception surrounding space exploration is that humanity's pursuit of interplanetary travel, such as missions to Mars, is an escape from Earth. In reality, this endeavour offers an invaluable opportunity to address critical biomedical challenges here at home.
Carina Kern, Tina Woods, Keith Siew
wiley +1 more source
Body composition and lipodystrophy in prepubertal HIV-infected children
Objective: To identify lipodystrophy in prepubertal HIV-infected children using anthropometric parameters and body composition assessment. Methods: Cross-sectional study including 40 prepubertal HIV-infected children of both genders seen at the Care ...
Cecilia Zanin Palchetti +5 more
doaj +1 more source
Prevalence of lipodystrophy associated with human recombinant insulin
Background and Purpose: Lipodystrophy is potentially a clinical adverse effect, associated with insulin therapy and is believed that usage of human recombinant insulin’s is associated with decreasing prevalence of Lipodystrophy.
S. Akbarzadeh +3 more
doaj
In this study, we analysed the mutation spectrum in subjects with suspected lipodystrophy using a targeted Next-generation sequencing (NGS) approach. Subjects with suspected lipodystrophy were for screened six genes (AGPAT2, BSCL2, LMNA, PPARG, ZMPSTE24,
Remya Rajan +8 more
doaj +1 more source
Does lipodystrophy affect adherence? The cross-sectional GRAAL study
Previous studies have shown that patients evaluation of lipodystrophy and measurements of adherence is accurate. The cross sectional GRAAL study aims at analysing the impact of lipodystrophy on drug adherence, measured by self-assessment ...
Della Loggia P. +14 more
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