Results 81 to 90 of about 30,524 (205)

The Trust‐Link Relational Transition Model: A Unitary Caring Framework for Youth With HIV Transitioning to Adult Healthcare

open access: yesJournal of Advanced Nursing, Volume 82, Issue 5, Page 5479-5492, May 2026.
ABSTRACT Aims To develop a conceptual model integrating Robinson's Theory of Trust and Watson's Caritas Processes to guide trust‐building approaches and caring practices that support adolescents and young adults with HIV during the healthcare transition from paediatric to adult care.
Emily Anne Barr, Sara Horton‐Deutsch
wiley   +1 more source

Impaired expression of mitochondrial and adipogenic genes in adipose tissue from a patient with acquired partial lipodystrophy (Barraquer-Simons syndrome): a case report

open access: yesJournal of Medical Case Reports, 2008
Introduction Acquired partial lipodystrophy or Barraquer-Simons syndrome is a rare form of progressive lipodystrophy. The etiopathogenesis of adipose tissue atrophy in these patients is unknown.
Guallar Jordi P   +9 more
doaj   +1 more source

Evaluation of subcutaneous proleukin (Interleukin-2) in a randomized international trial (ESPRIT): Geographical and gender differences in the baseline characteristics of participants [PDF]

open access: yes, 2006
Background: ESPRIT, is a phase III, open-label, randomized, international clinical trial evaluating the effects of subcutaneous recombinant interleukin-2 (rIL-2) plus antiretroviral therapy (ART) versus ART alone on HIV-disease progression and death in ...
Arduino, R.   +12 more
core   +3 more sources

Caspase‐6 Controls Lipid and Energy Metabolism in Diet‐Induced Obesity

open access: yesAdvanced Science, Volume 13, Issue 21, 13 April 2026.
This study reveals an unknown metabolic role of caspase‐6 beyond cell death. Caspase‐6 deficiency protects against HFD‐induced obesity by increasing energy expenditure, reducing inflammation, and improving glucose metabolism. Mechanistically, caspase‐6 cleaves PPARγ and SP1 to suppress ATGL expression.
Abhishek Gupta   +7 more
wiley   +1 more source

Berardinelli-Seip Syndrome [PDF]

open access: yes, 2011
We have reported two cases of Berardinelli-syndrome in a family which is a rare autosomal recessive disorder of the adipose tissue, originally described by Berardinelli and Seip, has been reported in approximately 120 patients of various ethnic origins ...
Dal, Sameer I, Patel, Hitesh
core   +1 more source

Adipocyte‐Derived Exosomal miR‐5099 Mitigates M1 Macrophage Polarization and Adipose Inflammation via c‐Met/NF‐κB Axis to Improve Metabolic Health

open access: yesAdvanced Science, Volume 13, Issue 24, 27 April 2026.
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang   +9 more
wiley   +1 more source

Misclassification of Diabetes Mellitus in Resource‐Limited Settings: A Case Study and Clinical Review

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Recent refinements to diabetes classification frameworks have inadvertently complicated the diagnostic process, particularly in resource‐limited settings. This case demonstrates that meticulous phenotyping, judicious selection of feasible investigations, and disciplined clinical inference are essential to avoid misclassification and deliver ...
Issakwisa Mwakyula   +2 more
wiley   +1 more source

Giant Cervical Lipoma: The First Documented Case Report From Ethiopia

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Lipomas are benign tumors composed of adipose tissue that can occur throughout the body, although a smaller proportion arise in the head and neck region. While typically small, lipomas are classified as giant when exceeding 10 cm. We present a case of a giant posterior cervical lipoma measuring approximately 20 cm, which to our knowledge is ...
Kinfemicheal Tilahun Yigzaw   +6 more
wiley   +1 more source

Heterozygous frameshift mutations (MIM 601047) in patients with atypical partial lipodystrophy and hypertriglyceridemia [PDF]

open access: yes, 2008
Background Mice with a deleted Cav1 gene encoding caveolin-1 develop adipocyte abnormalities and insulin resistance. From genomic DNA of patients with atypical lipodystrophy and hypertriglyceridemia who had no mutations in any known lipodystrophy gene ...
Henian Cao   +3 more
core   +1 more source

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