Results 131 to 140 of about 39,706 (298)
PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection. [PDF]
Chronic gut inflammatory diseases are associated with disruption of intestinal epithelial barriers and impaired mucosal immunity. HIV-1 (HIV) causes depletion of mucosal CD4+ T cells early in infection and disruption of gut epithelium, resulting in ...
Arredondo, Juan+13 more
core
Background Lipodystrophies are rare acquired and genetic disorders characterized by the complete or partial absence of body fat with a line of metabolic disorders.
Shirouchi Bungo+6 more
doaj +1 more source
Prevalence of lipodystrophy associated with human recombinant insulin
Background and Purpose: Lipodystrophy is potentially a clinical adverse effect, associated with insulin therapy and is believed that usage of human recombinant insulin’s is associated with decreasing prevalence of Lipodystrophy.
S. Akbarzadeh+3 more
doaj
BackgroundThe aim of this study was to establish the prevalence of lipodystrophy and its association to cumulative exposure to antiretroviral drugs.MethodWe conducted a cross sectional study in all HIV- infected patients attending the HIV clinic in the ...
A. Alikhani+5 more
semanticscholar +1 more source
Cultivation of \u3cem\u3eTropheryma whipplei\u3c/em\u3e from Cerebrospinal Fluid [PDF]
Whipple disease (WD) is a systemic disorder caused by the bacterium Tropheryma whipplei. Since the recognition of a bacterial etiology in 1961, many attempts have been made to cultivate this bacterium in vitro.
Fredricks, David N.+5 more
core +1 more source
Body composition and lipodystrophy in prepubertal HIV-infected children
Objective: To identify lipodystrophy in prepubertal HIV-infected children using anthropometric parameters and body composition assessment. Methods: Cross-sectional study including 40 prepubertal HIV-infected children of both genders seen at the Care ...
Cecilia Zanin Palchetti+5 more
doaj +1 more source
Effects of metreleptin on proteinuria in patients with lipodystrophy.
CONTEXT Patients with lipodystrophy have high prevalence of proteinuria. OBJECTIVE To assess kidney disease in patients with generalized (GLD) versus partial lipodystrophy (PLD), and effects metreleptin on proteinuria in patients with lipodystrophy ...
Ho Lim Lee+6 more
semanticscholar +1 more source
Pediatric Obesity: Influence on Drug Dosing and Therapeutics [PDF]
Obesity is an ongoing global health concern and has only recently been recognized as a chronic disease of energy homeostasis and fuel partitioning. Obesity afflicts 17% of US children and adolescents.
Ameer, Barbara, PharmD, MBA, BCPS, FCP+1 more
core +1 more source
Adult-Onset Acquired Partial Lipodystrophy Accompanied by Rheumatoid Arthritis
Lipodystrophy is a group of metabolic disorders, possibly caused by autoimmune disease. In this report, we describe a case of adult-onset acquired partial lipodystrophy accompanied by rheumatoid arthritis without a family history.
Yusuke Muto+5 more
doaj +1 more source
Autoantibodies against perilipin 1 as a cause of acquired generalized lipodystrophy [PDF]
Acquired generalized lipodystrophy (AGL) is a rare condition characterized by an altered distribution of adipose tissue and predisposition to develop hepatic steatosis and fibrosis, diabetes, and hypertriglyceridemia.
Aparicio, Verónica+6 more
core +3 more sources