Results 11 to 20 of about 17,675 (181)

Mitochondrial contribution to lipofuscin formation

open access: yesRedox Biology, 2017
Mitochondria have been in the focus of oxidative stress and aging research for decades due to their permanent production of ROS during the oxidative phosphorylation.
Jeannette König   +6 more
doaj   +3 more sources

Bone marrow lipofuscin [PDF]

open access: yesJournal of Clinical Pathology, 1972
Lipofuscins are commonly present in the macrophages of the marrow. In unstained preparations they may be confused with haemosiderin, but they are readily distinguished by fluorescence microscopy. In contrast to the belief that lipofuscins are a manifestation of senility, no age dependence has been demonstrated ...
K G, Clark, W M, Davidson
openaire   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Frontal lobe epilepsy with focal neuronal lipofuscinosis – Case report of a rare entity

open access: yesEpilepsy & Behavior Reports, 2020
Focal neuronal lipofuscinosis is a unique neuronal pathology, characterised by accumulation of lipofuscin within dysmorphic neurons. We report a case of 12-year-old female with drug resistant epilepsy since one and a half years of age.
Radhika Mhatre   +5 more
doaj   +1 more source

Automatic quantification of myocardial remodeling features in human ventricular tissue from label-free microscopy

open access: yesSTAR Protocols, 2023
Summary: The procedures used routinely for collagen and lipofuscin evaluation are, in many cases, qualitative, observer dependent, and disregard spatial distribution.
Laura García-Mendívil   +4 more
doaj   +1 more source

Effect of season and behavioral activity on the hypopharyngeal glands of three honey bee Apis mellifera L. races under stressful climatic conditions of central Saudi Arabia [PDF]

open access: yesJournal of Hymenoptera Research, 2019
Honey production gains are needed to deal with high demand in Saudi Arabia. The honey bee races are facing stressful hot-arid weather conditions that can affect different aspects of physiology and behavior.
Hussain Ali   +5 more
doaj   +3 more sources

Analysis of Retinol Binding Protein 4 and ABCA4 Gene Variation in Non-Neovascular Age-Related Macular Degeneration

open access: yesDiagnostics, 2023
Age-related macular degeneration (AMD) may be associated with ABCA4 variants and is characterized by the accumulation of visual cycle-byproduct lipofuscin.
Hung-Da Chou   +9 more
doaj   +1 more source

Cell Autofluorescence and Lipofuscin [PDF]

open access: yesFrontiers in Medicine, 2015
I was greatly impressed by an article recently published in Nature Methods (1), in which intracellular autofluorescence was characterized as a biomarker for epithelial cancer stem cells (CSCs). Interestingly, this epithelial CSC-specific autofluorescence was also associated with a highly invasive and chemoresistant phenotype.
openaire   +4 more sources

Role of macrophages in age-related oxidative stress and lipofuscin accumulation in mice

open access: yesRedox Biology, 2017
The age-related changes in the immune functions (immunosenescence) may be mediated by an increase of oxidative stress and damage affecting leukocytes.
Carmen Vida   +5 more
doaj   +1 more source

Autofluorescence in freshly isolated adult human liver sinusoidal cells

open access: yesEuropean Journal of Histochemistry, 2021
Autofluorescent granules of various sizes were observed in primary human liver endothelial cells (LSECs) upon laser irradiation using a wide range of wavelengths.
Anett Kristin Larsen   +7 more
doaj   +1 more source

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