Results 1 to 10 of about 18,102 (192)

Detection of Alloxan induced Lipofuscin pigmentation in the cells of renal tubule of diabetic rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2000
Objective: Diabetes mellitus is a metabolic disease due to failure in insulin secretion function. Kidney is a target organ in diabetes. Diabetic nephropathy is a major cause of end stage renal disease and resulting in increased morbidity and mortality of
M Pour Ghasem, M Jalali, M Nikravesh, M Behnam Rasoli, N Aminian   +4 more
doaj  

JAPANESE QUAIL (COTURNIX JAPONICA) AS A MODEL OF ACCELERATED AGING OF HUMAN RETINAL PROCESSES. REPORT 1. ASSESSMENT OF THE AGE RPE LIPOFUSCIN ACCUMULATION DEPENDING ON THE RETINAL AMOUNT OF OXYCAROTENOIDS

Офтальмохирургия, 2015
Purpose. Using the eyes of quails C. japonic as a model system to evaluate age-related accumulation of lipofuscin granules in the cells of the retinal pigment epithelium depending on the level of oxycarotenoids content in the retina and in the retinal ...
P. P. Zak, A. V. Zykova, N. N. Trofimova, M. A. Ostrovsky   +3 more
doaj  

Effect of ocular magnification on macular measurements made using spectral domain optical coherence tomography

Indian Journal of Ophthalmology, 2015
Aim: The aim of the present study was to study the effect of ocular magnification on macular measurements made using spectral domain optical coherence tomography (OCT).
Mohana Kuppuswamy Parthasarathy, Muna Bhende   +1 more
doaj   +1 more source

Japanese quail (Coturnix japonica) as a model of accelerated aging of human retinal processes. Report 1. Assessment of the age RPE lipofuscin accumulation depending on the retinal amount of oxycarotenoids

Офтальмохирургия, 2013
Purpose. Using the eyes of quails C. japonic as a model system to evaluate age-related accumulation of lipofuscin granules in the cells of the retinal pigment epithelium depending on the level of oxycarotenoids content in the retina and in the retinal ...
P.P. Zak, A.V. Zykova, N.N. Trofimova, M.A. Ostrovsky   +3 more
doaj  

Choroidal thickness changes after dynamic exercise as measured by spectral-domain optical coherence tomography

Indian Journal of Ophthalmology, 2015
Purpose: To measure the choroidal thickness (CT) after dynamic exercise by using enhanced depth imaging optical coherence tomography (EDI-OCT). Materials and Methods: A total of 19 healthy participants performed 10 min of low-impact, moderate-intensity ...
Nihat Sayin, Necip Kara, Gokhan Pekel, Hasan Altinkaynak   +3 more
doaj   +1 more source

Lighting Up the Retina: Fundus Autofluorescence Imaging in Retinal and Choroidal Diseases

TNOA Journal of Ophthalmic Science and Research
Fundus autofluorescence (FAF) is a non-invasive imaging method that maps normal and abnormal retinal fluorophores, mainly lipofuscin. Although researched for decades, its major clinical use expanded significantly only in recent years. It has emerged as a
Kushal Delhiwala, Keshavi Shah
doaj   +1 more source

Metformin attenuates cuprizone-induced mitochondrial dysfunction and senescence-associated changes in primary neuronal cells

Cell Structure and Function
Mitochondrial dysfunction and cellular senescence are key features of brain aging and neurodegenerative diseases. Cuprizone (CPZ), a mitochondrial toxin, induces oxidative stress, abnormal lipid metabolism, and iron accumulation in neurons and ...
Yeojin Kim, Hyunbum Jeon, Sun-Yeong Gwon, Sehyun Chae, Ji Young Mun   +4 more
doaj   +1 more source

Resistance training does not increase myocellular garbage dumps: A pilot study on lipofuscin in skeletal muscle fibers of resistance trained young men

Physiological Reports
Lipofuscin (LF) is an intracellular aggregate associated with proteostatic impairments, especially prevalent in nondividing skeletal muscle fibers. Reactive oxygen species (ROS) drive LF‐formation. Resistance training (RT) improves muscle performance but
Daniel Jacko, Lukas Masur, Kirill Schaaf, Jonas Zacher, Käthe Bersiner, Markus deMarées, Wilhelm Bloch, Sebastian Gehlert   +7 more
doaj   +1 more source

Exogenous Iron Induces Mitochondrial Lipid Peroxidation, Lipofuscin Accumulation, and Ferroptosis in H9c2 Cardiomyocytes

Biomolecules
Lipid peroxidation plays an important role in various pathologies and aging, at least partially mediated by ferroptosis. The role of mitochondrial lipid peroxidation during ferroptosis remains poorly understood.
Konstantin G. Lyamzaev, He Huan, Alisa A. Panteleeva, Ruben A. Simonyan, Armine V. Avetisyan, Boris V. Chernyak   +5 more
doaj   +1 more source

Spotlight on fundus autofluorescence

Clinical Optometry, 2018
Ana M Calvo-Maroto,1 Alejandro Cerviño2 1Department of Ophthalmology, Clínica Universidad de Navarra, University of Navarra, Madrid, Spain; 2Optometry Research Group, Department of Optics and Optometry and Vision Sciences, University of ...
Calvo-Maroto AM, Cerviño A
doaj