Results 31 to 40 of about 18,102 (192)
Autofluorescence in freshly isolated adult human liver sinusoidal cells
European Journal of Histochemistry, 2021 Autofluorescent granules of various sizes were observed in primary human liver endothelial cells (LSECs) upon laser irradiation using a wide range of wavelengths.
Anett Kristin Larsen +7 more
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Lipofuscin Hypothesis of Alzheimer’s Disease [PDF]
Dementia and Geriatric Cognitive Disorders Extra, 2011 The primary culprit responsible for Alzheimer’s disease (AD) remains unknown. Aβ protein has been identified as the main component of amyloid of senile plaques, the hallmark lesion of AD, but it is not definitively established whether the formation of extracellular Aβ deposits is the absolute harbinger of the series of pathological events that hit the ...
Giorgio Giaccone +3 more
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Parity-Dependent Hemosiderin and Lipofuscin Accumulation in the Reproductively Aged Mouse Ovary
Analytical Cellular Pathology, 2018 The progressive decline of the ovarian follicle pool leads to reproductive ageing. The latter is accompanied by age-related disorders, including various types of cancer.
Ulises Urzua +4 more
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Immunochemical detection of a lipofuscin-like fluorophore derived from malondialdehyde and lysine
Journal of Lipid Research, 2001 The accumulation of fluorescent age pigment or lipofuscin is a frequently observed age-associated cellular alteration in a variety of postmitotic cells of many species. These pigments are observed within granules composed, in part, of damaged protein and
Satoshi Yamada +9 more
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LIPOFUSCIN ROLE IN INVOLUTIVE AND PATHOLOGICAL PROCESSES [PDF]
Саратовский научно-медицинский журнал, 2009 The modern data on the lipofuscin role in the processes of intracellular exchange have been analysed in the review. The ambiguity of the interpretation of lipofuscin accumulation according to its importance in involutive and pathological processes has ...
Maslyakova, A.A. Efimov
doaj
BMC Nephrology, 2019 Background Lipofuscin deposition is a characteristic manifestation of aging. There is very limited literature in humans and in animals describing these deposits in native kidneys.
Vivian W. Y. Leung +3 more
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Cannabinoid Receptor 2 Alters Social Memory and Microglial Activity in an Age-Dependent Manner
Molecules, 2021 Physiological brain aging is characterized by gradual, substantial changes in cognitive ability, accompanied by chronic activation of the neural immune system.
Joanna Agnieszka Komorowska-Müller +4 more
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Antioxidants, 2021 In humans, alterations of circadian rhythms and autophagy are linked to metabolic, cardiovascular and neurological dysfunction. Autophagy constitutes a specific form of cell recycling in many eukaryotic cells.
Jan Hendrik Börner +2 more
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Closing the Loop: High‐Precision 3D Photofabrication in Living Tissues
Advanced Science, EarlyView.Writing 3D microstructures inside living tissue demands more than laser access; It demands information. Hierarchical sensing captures thermal and mechanical states across pulse‐train, voxel, and structure timescales, feeding a controller that steers the laser in real time.
Amirbahador Zeynali +2 more
wiley +1 more source
Cell Autofluorescence and Lipofuscin [PDF]
Frontiers in Medicine, 2015 I was greatly impressed by an article recently published in Nature Methods (1), in which intracellular autofluorescence was characterized as a biomarker for epithelial cancer stem cells (CSCs). Interestingly, this epithelial CSC-specific autofluorescence was also associated with a highly invasive and chemoresistant phenotype.
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