Results 31 to 40 of about 28,509 (234)
Outer Retinal Structure in Best Vitelliform Macular Dystrophy [PDF]
, 2013 Importance Demonstrating the utility of adaptive optics scanning light ophthalmoscopy (AOSLO) to assess outer retinal structure in Best vitelliform macular dystrophy (BVMD).
Carroll, Joseph +7 more
core +3 more sources
Parity-Dependent Hemosiderin and Lipofuscin Accumulation in the Reproductively Aged Mouse Ovary
Analytical Cellular Pathology, 2018 The progressive decline of the ovarian follicle pool leads to reproductive ageing. The latter is accompanied by age-related disorders, including various types of cancer.
Ulises Urzua +4 more
doaj +1 more source
Photoreceptor Inner Segment Morphology in Best Vitelliform Macular Dystrophy [PDF]
, 2016 PURPOSE To characterize outer retina structure in best vitelliform macular dystrophy (BVMD) and to determine the effect of macular lesions on overlying and adjacent photoreceptors.
Carroll, Joseph +7 more
core +2 more sources
Immunochemical detection of a lipofuscin-like fluorophore derived from malondialdehyde and lysine
Journal of Lipid Research, 2001 The accumulation of fluorescent age pigment or lipofuscin is a frequently observed age-associated cellular alteration in a variety of postmitotic cells of many species. These pigments are observed within granules composed, in part, of damaged protein and
Satoshi Yamada +9 more
doaj +1 more source
In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques. [PDF]
, 2017 Nonhuman primates are the only mammals to possess a true macula similar to humans, and spontaneously develop drusenoid lesions which are hallmarks of age-related macular degeneration (AMD).
Cunefare, David +8 more
core +2 more sources
Cannabinoid Receptor 2 Alters Social Memory and Microglial Activity in an Age-Dependent Manner
Molecules, 2021 Physiological brain aging is characterized by gradual, substantial changes in cognitive ability, accompanied by chronic activation of the neural immune system.
Joanna Agnieszka Komorowska-Müller +4 more
doaj +1 more source
The Evolving Role of CD8+CD28- Immunosenescent T Cells in Cancer Immunology [PDF]
, 2019 Functional, tumor-specific CD8+ cytotoxic T lymphocytes drive the adaptive immune response to cancer. Thus, induction of their activity is the ultimate aim of all immunotherapies.
Dey, Mahua +4 more
core +1 more source
LIPOFUSCIN ROLE IN INVOLUTIVE AND PATHOLOGICAL PROCESSES [PDF]
Саратовский научно-медицинский журнал, 2009 The modern data on the lipofuscin role in the processes of intracellular exchange have been analysed in the review. The ambiguity of the interpretation of lipofuscin accumulation according to its importance in involutive and pathological processes has ...
Maslyakova, A.A. Efimov
doaj
Antioxidants, 2021 In humans, alterations of circadian rhythms and autophagy are linked to metabolic, cardiovascular and neurological dysfunction. Autophagy constitutes a specific form of cell recycling in many eukaryotic cells.
Jan Hendrik Börner +2 more
doaj +1 more source
Cell Autofluorescence and Lipofuscin [PDF]
Frontiers in Medicine, 2015 I was greatly impressed by an article recently published in Nature Methods (1), in which intracellular autofluorescence was characterized as a biomarker for epithelial cancer stem cells (CSCs). Interestingly, this epithelial CSC-specific autofluorescence was also associated with a highly invasive and chemoresistant phenotype.
openaire +4 more sources