Results 51 to 60 of about 28,509 (234)

Impact of alpha-tocopherol deficiency and supplementation on sacrocaudalis and gluteal muscle fiber histopathology and morphology in horses. [PDF]

open access: yes, 2019
BackgroundA subset of horses deficient in alpha-tocopherol (α-TP) develop muscle atrophy and vitamin E-responsive myopathy (VEM) characterized by mitochondrial alterations in the sacrocaudalis dorsalis medialis muscle (SC).ObjectivesTo quantify muscle ...
Bookbinder, Lauren   +10 more
core   +2 more sources

Liver disease in Shwachman‐Diamond syndrome: A comprehensive characterization across the age spectrum

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Shwachman‐Diamond syndrome (SDS) is an inherited bone marrow failure disorder, and its hepatic phenotype is poorly defined. Our objective was to systematically characterize the prevalence, features, and outcomes of liver injury in a multicenter SDS cohort. Methods Retrospective registry study of 171 patients with biallelic Shwachman‐
Jane Koo   +16 more
wiley   +1 more source

Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin. [PDF]

open access: yes, 2004
Daily phagocytosis by the retinal pigment epithelium (RPE) of spent photoreceptor outer segment fragments is critical for vision. In the retina, early morning circadian photoreceptor rod shedding precedes synchronized uptake of shed photoreceptor ...
Brodie, Scott E   +5 more
core   +1 more source

Management Of Stargardt’s Disease Through Ayurvedic Science

open access: yesDelhi Journal of Ophthalmology, 2018
Stargardt’s disease is a hereditary disorder of the retina. There is a gradual loss of vision during childhood or adolescence and in a few cases, vision loss may be noticed in adulthood.
Santosh Kumar Shaw   +2 more
doaj   +1 more source

Anti-aging Effects and Mechanisms of Recombinant Human-derived Collagen on Aging Mouse Induced by D-Galactose

open access: yesShipin gongye ke-ji, 2023
In order to explore the anti-aging effect and mechanism of recombinant recombinant human-derived collagen (RHC), the aging mouse model was constructed through 300 mg/kg D-galactose intraperitoneal injection, and different doses of RHC were used to study ...
Jia LI   +5 more
doaj   +1 more source

Exploring the Impact of Polystyrene Microplastic Beads on Male Gonads of the Marine Mussel, Mytilus galloprovincialis

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese   +13 more
wiley   +1 more source

Immunostaining of skeletal tissues [PDF]

open access: yes, 2011
Peer ...
De Bari, Cosimo, Kurth, Tobias B
core   +1 more source

Crosstalk between the Rod Outer Segments and Retinal Pigmented Epithelium in the Generation of Oxidative Stress in an In Vitro Model

open access: yesCells, 2023
Dysfunction of the retinal pigment epithelium (RPE) is associated with several diseases characterized by retinal degeneration, such as diabetic retinopathy (DR).
Silvia Ravera   +5 more
doaj   +1 more source

Mesopic microperimetry in Stargardt disease: Application and reliability

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Mesopic microperimetry (mMP) is a promising functional endpoint in clinical trials for Stargardt disease type 1 (STGD1). This study evaluated the test–retest variability of mMP and influencing factors, which is essential for ensuring reliability in future STGD1 trials.
Sybren H. Kootstra   +12 more
wiley   +1 more source

\u3cem\u3eIn vivo\u3c/em\u3e Dark-field Imaging of the Retinal Pigment Epithelium Cell Mosaic [PDF]

open access: yes, 2013
Non-invasive reflectance imaging of the human RPE cell mosaic is demonstrated using a modified confocal adaptive optics scanning light ophthalmoscope (AOSLO). The confocal circular aperture in front of the imaging detector was replaced with a combination
Dubra, Alfredo   +2 more
core   +1 more source

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