Results 61 to 70 of about 28,509 (234)

Oxidative Stress in Aging Human Skin

Biomolecules, 2015
Oxidative stress in skin plays a major role in the aging process. This is true for intrinsic aging and even more for extrinsic aging. Although the results are quite different in dermis and epidermis, extrinsic aging is driven to a large extent by ...
Mark Rinnerthaler, Johannes Bischof, Maria Karolin Streubel, Andrea Trost, Klaus Richter   +4 more
doaj   +1 more source

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Acta Ophthalmologica, EarlyView.
Abstract Purpose To measure the progression of geographic atrophy (GA) in subjects with age‐related macular degeneration (AMD) in a natural history study. Methods We analysed fundus autofluorescence (FAF) images using a semiautomatic method (RegionFinder) to quantify the GA area in a monocentric study.
Philippe Valmaggia, Georg Ansari, Nadja Inglin, Nils Schärer, Hanna Zuche, Chrysoula Gabrani, Faady Yahya, Marco Cattaneo, Kristina Pfau, Andrea Giani, Marieh Esmaeelpour, Taffeta Chingning Yamaguchi, Christian Prünte, Hendrik P. N. Scholl, Nicolas Feltgen, Leopold Schmetterer, Maximilian Pfau, Peter M. Maloca   +17 more
wiley   +1 more source

Mitochondrial dysfunction and oxidative stress in patients with chronic kidney disease. [PDF]

, 2016
Mitochondria abnormalities in skeletal muscle may contribute to frailty and sarcopenia, commonly present in patients with chronic kidney disease (CKD).
Billings, Frederic T, Bojanowski, Matthew T, Brown, Nancy J, Gamboa, Jorge L, Gilliam, Laura A, Himmelfarb, Jonathan, Ikizler, T Alp, Roberts, L Jackson, Roshanravan, Baback, Yu, Chang   +9 more
core   +1 more source

Oxidized protein aggregate lipofuscin impairs cardiomyocyte contractility via late-stage autophagy inhibition

Redox Biology
Aging of the heart is accompanied by impairment of cardiac structure and function. At molecular level, autophagy plays a crucial role in preserving cardiac health.
Sophia Walter, Steffen P. Häseli, Patricia Baumgarten, Stefanie Deubel, Tobias Jung, Annika Höhn, Christiane Ott, Tilman Grune   +7 more
doaj   +1 more source

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen, Jenni Martinez Villarruel Hinnerskov, Miranda Maung, Aubin Mutschler, SriniVas Sadda, Torben Lykke Sørensen   +5 more
wiley   +1 more source

Lipid metabolic perturbation is an early-onset phenotype in adult spinster mutants: a Drosophila model for lysosomal storage disorders [PDF]

, 2017
Intracellular accumulation of lipids and swollen dysfunctional lysosomes are linked to several neurodegenerative diseases, including lysosomal storage disorders (LSD).
Acharya JK, Acharya U, Avinash Khandelwal, Bilen J, Billeter JC, Brankatschk M, Carvalho M, Carvalho M, Cheng H, Cutler RG, Dasgupta U, Dermaut B, Dominik Schwudke, Ejsing CS, Fergestad T, Georgakopoulou EA, Ghosh A, Gray DA, Guan XL, Gutierrez E, Han X, Hebbar S, Hebbar S, Herzog R, Hickey AJ, Hindle S, Hindle SJ, Hoglinger D, Ito M, Jang S, Joanne Y. Yew, Julie Brill, Kawahara A, Kumarasamy SK, Lim A, Liu L, Lloyd-Evans E, Matyash V, Mi H, Milton VJ, Nakano Y, Osborne N, Palm W, Panchal M, Pantoja M, R. Jayashree, Rohrbough J, Rong Y, Samantha J. Hindle, Sampaio JL, Sarita Hebbar, Sasamura T, Schneider CA, Schwudke D, Sean T. Sweeney, Seppo A, Shevchenko A, Shevchenko A, Starostina E, Stern CA, Sweeney ST, te Vruchte D, Thomas PD, Venkatachalam K, Xu Y, Yew JY, Yin Ning Chiang, Zigdon H   +67 more
core   +1 more source

Longevity and Growth of the Crabs Callinectes sapidus and Callinectes rathbunae (Decapoda: Portunidae) in Paraíso Tabasco Mexico

Acta Zoologica, EarlyView.
ABSTRACT Individual growth models are important in fisheries of natural populations and can be incorporated in production models to estimate their maximum sustainable yield. Blue crab species, Callinectes sapidus and Callinectes rathbunae were obtained in the Mecoacán lagoon, Paraíso, Tabasco Mexico by “nasa” and “yahual” nets. Biometric values such as
Candelario Jiménez‐Olivares, Sergio Cházaro‐Olvera, Fernando Álvarez‐Noguera, Mixtli Crisóstomo‐Pérez, Verónica Mitsui Saito‐Quezada, Isaías Hazarmabeth Salgado‐Ugarte   +5 more
wiley   +1 more source

Fundus autofluorescence applications in retinal imaging

Indian Journal of Ophthalmology, 2015
Fundus autofluorescence (FAF) is a relatively new imaging technique that can be used to study retinal diseases. It provides information on retinal metabolism and health. Several different pathologies can be detected.
Andrea Gabai, Daniele Veritti, Paolo Lanzetta   +2 more
doaj   +1 more source

Pulmonary alveolar proteinosis after lung transplantation

Respirology Case Reports, 2020
We report the case of a 69‐year‐old man five‐month post double lung transplant for idiopathic pulmonary fibrosis (IPF) who presented with progressive breathlessness, loss of lung function, and diffuse ground glass shadowing on the chest computed ...
Chandima Divithotawela, Simon H. Apte, Maxine E. Tan, Tharushi A. De Silva, Daniel C. Chambers   +4 more
doaj   +1 more source

Orchestrated molecular changes of proliferative, migratory‐fibrillar, synaptic, and postmigratory compartments align with precocious cortex‐type specification in the early human pallium

Journal of Anatomy, EarlyView.
Early human cortical development is organized by transient cellular compartments that define cortical types before mature layers form. Analysis of the human fetal pallium (7.5–15 PCW) shows distinct spatiotemporal trajectories for the archicortex, mesocortex, and neocortex, with delayed but accelerated differentiation in allocortical regions.
Janja Kopić, Fran Božić, Alisa Junaković Munjas, Željka Krsnik, Ivica Kostović   +4 more
wiley   +1 more source