Results 71 to 80 of about 17,764 (195)
Senolytics and exercise: Dual modalities for rejuvenating muscle
The Journal of Physiology, EarlyView.Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Indian Journal of Ophthalmology, 2015 Aim: The aim of the present study was to study the effect of ocular magnification on macular measurements made using spectral domain optical coherence tomography (OCT).
Mohana Kuppuswamy Parthasarathy +1 more
doaj +1 more source
Journal of the Science of Food and Agriculture, Volume 106, Issue 12, Page 7002-7014, September 2026.Abstract BACKGROUND Inhibitors of angiotensin‐converting enzyme (ACE) are used in pharmaceuticals and functional foods. Captopril, a well‐known ACE inhibitor, extends the lifespan of the nematode Caenorhabditis elegans. Bioactive peptides derived from food sources are considered safe ACE inhibitors.
Issei Yokoyama +6 more
wiley +1 more source
Офтальмохирургия, 2015 Purpose. Using the eyes of quails C. japonic as a model system to evaluate age-related accumulation of lipofuscin granules in the cells of the retinal pigment epithelium depending on the level of oxycarotenoids content in the retina and in the retinal ...
P. P. Zak +3 more
doaj
Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION Astrocyte dysfunction is central to Alzheimer's disease (AD), yet expression patterns of astrocytic markers remain poorly defined. We measured Aquaporin‐4 (AQP4) and glial fibrillary acidic protein (GFAP) in post‐mortem frontal cortex of AD patients and controls across BrainNet Europe (BNE) stages.
Harry Alexopoulos +8 more
wiley +1 more source
Офтальмохирургия, 2013 Purpose. Using the eyes of quails C. japonic as a model system to evaluate age-related accumulation of lipofuscin granules in the cells of the retinal pigment epithelium depending on the level of oxycarotenoids content in the retina and in the retinal ...
P.P. Zak +3 more
doaj
Glia, Volume 74, Issue 8, August 2026.The Alzheimer's disease protective PLCG2 P522R variant protects against amyloid‐induced synapse loss independently of amyloid load, promotes increased plaque compaction, and is associated with enhanced microglial engagement with diffuse amyloid. ABSTRACT The Alzheimer's disease protective P522R PLCG2 coding variant (rs72824905) is downstream of TREM2 ...
Ryan J. Bevan +9 more
wiley +1 more source
Indian Journal of Ophthalmology, 2015 Purpose: To measure the choroidal thickness (CT) after dynamic exercise by using enhanced depth imaging optical coherence tomography (EDI-OCT). Materials and Methods: A total of 19 healthy participants performed 10 min of low-impact, moderate-intensity ...
Nihat Sayin +3 more
doaj +1 more source
Journal of Cellular Physiology, Volume 241, Issue 8, August 2026.ABSTRACT Ageing is a major risk factor for degenerative diseases, including sarcopenia, which is characterized by a progressive loss of skeletal muscle mass and function, frailty, and is associated with increased mortality. Skeletal muscle regeneration relies on muscle stem cells and efficient communication with cellular microenvironment.
Juan Diego Hernández‐Camacho +1 more
wiley +1 more source
Lighting Up the Retina: Fundus Autofluorescence Imaging in Retinal and Choroidal Diseases
TNOA Journal of Ophthalmic Science and ResearchFundus autofluorescence (FAF) is a non-invasive imaging method that maps normal and abnormal retinal fluorophores, mainly lipofuscin. Although researched for decades, its major clinical use expanded significantly only in recent years. It has emerged as a
Kushal Delhiwala, Keshavi Shah
doaj +1 more source