Results 81 to 90 of about 17,237 (190)

Understanding RPE Lipofuscin [PDF]

Investigative Opthalmology & Visual Science, 2013
Janet R, Sparrow, John E, Dowling, Dean, Bok   +2 more
openaire   +2 more sources

Specific Lipid Peroxidation Products in Erythrocytes and Their Relationship to the Pathogenesis of Alzheimer's Disease

Journal of Cellular and Molecular Medicine, Volume 30, Issue 5, March 2026.
ABSTRACT Alzheimer's disease (AD) is a highly complex and multifactorial disorder in which oxidative stress acts as a key amplifying mechanism in the disease progression. Lipofuscin‐like pigments (LFP), end products of lipid peroxidation, reflect oxidative damage and are capable of crossing the blood–brain barrier into the circulation.
Lenka Martináková, Zuzana Chmátalová, Kateřina Veverová, Vanesa Jurášová, Alžběta Katonová, Martina Laczó, Jan Laczó, Martin Vyhnálek, Jakub Hort, Alice Skoumalová   +9 more
wiley   +1 more source

Resistance training does not increase myocellular garbage dumps: A pilot study on lipofuscin in skeletal muscle fibers of resistance trained young men

Physiological Reports
Lipofuscin (LF) is an intracellular aggregate associated with proteostatic impairments, especially prevalent in nondividing skeletal muscle fibers. Reactive oxygen species (ROS) drive LF‐formation. Resistance training (RT) improves muscle performance but
Daniel Jacko, Lukas Masur, Kirill Schaaf, Jonas Zacher, Käthe Bersiner, Markus deMarées, Wilhelm Bloch, Sebastian Gehlert   +7 more
doaj   +1 more source

JAPANESE QUAIL (COTURNIX JAPONICA) AS A MODEL OF ACCELERATED AGING OF HUMAN RETINAL PROCESSES. REPORT 1. ASSESSMENT OF THE AGE RPE LIPOFUSCIN ACCUMULATION DEPENDING ON THE RETINAL AMOUNT OF OXYCAROTENOIDS

Офтальмохирургия, 2015
Purpose. Using the eyes of quails C. japonic as a model system to evaluate age-related accumulation of lipofuscin granules in the cells of the retinal pigment epithelium depending on the level of oxycarotenoids content in the retina and in the retinal ...
P. P. Zak, A. V. Zykova, N. N. Trofimova, M. A. Ostrovsky   +3 more
doaj  

Japanese quail (Coturnix japonica) as a model of accelerated aging of human retinal processes. Report 1. Assessment of the age RPE lipofuscin accumulation depending on the retinal amount of oxycarotenoids

Офтальмохирургия, 2013
Purpose. Using the eyes of quails C. japonic as a model system to evaluate age-related accumulation of lipofuscin granules in the cells of the retinal pigment epithelium depending on the level of oxycarotenoids content in the retina and in the retinal ...
P.P. Zak, A.V. Zykova, N.N. Trofimova, M.A. Ostrovsky   +3 more
doaj  

Exogenous Iron Induces Mitochondrial Lipid Peroxidation, Lipofuscin Accumulation, and Ferroptosis in H9c2 Cardiomyocytes

Biomolecules
Lipid peroxidation plays an important role in various pathologies and aging, at least partially mediated by ferroptosis. The role of mitochondrial lipid peroxidation during ferroptosis remains poorly understood.
Konstantin G. Lyamzaev, He Huan, Alisa A. Panteleeva, Ruben A. Simonyan, Armine V. Avetisyan, Boris V. Chernyak   +5 more
doaj   +1 more source

Understanding RPE Lipofuscin

Investigative Opthalmology & Visual Science, 2016
R Theodore, Smith, Sina, Farsiu, Michael, Allingham   +2 more
openaire   +2 more sources

Spotlight on fundus autofluorescence

Clinical Optometry, 2018
Ana M Calvo-Maroto,1 Alejandro Cerviño2 1Department of Ophthalmology, Clínica Universidad de Navarra, University of Navarra, Madrid, Spain; 2Optometry Research Group, Department of Optics and Optometry and Vision Sciences, University of ...
Calvo-Maroto AM, Cerviño A
doaj  

The triggered antioxidant response and corresponding metabolomics expression of Caenorhabditis elegans for chronic exposure to moxifloxacin and trace copper. [PDF]

Bioresour Bioprocess
Liu L, Liu Y, Tang M, Zhu M, Wang F, Lin K.   +5 more
europepmc   +1 more source

<i>In vivo</i> lipofuscin quantification by visible-light optical coherence tomography-based fundus autofluorescence imaging. [PDF]

iScience
Zhou R, Li Y, Wen R, Jiao S.
europepmc   +1 more source