Results 181 to 190 of about 75,579 (341)

An Application of a Large‐Scale, Data‐Driven Approach to Prioritize Compound‐Targeted Conditions in the Nutraceutical Space: Case Study of QuercefitTM (Quercetin Phytosome) Toward Unbalanced Lipid Conditions in Metabolically Challenged Adults

Molecular Nutrition &Food Research, EarlyView.
Quercetin, a bioactive flavonoid abundant in fruits and vegetables, exhibits antioxidant and anti‐inflammatory effects with potential benefits in metabolic health. Using a high‐throughput in‐silico repurposing pipeline previously validated in pharmaceutical studies, 33 quercetin gene‐expression signatures were systematically compared against more than ...
Loukia Lili, Sheena Smith, Laura Kunces, Riva Antonella, Pietro Allegrini, Stefano Togni, Serena Tongiani, Nate Rickard, Benjamin Readhead, Stephen Phipps, Bodi Zhang   +10 more
wiley   +1 more source

The pathogenesis of hepatic steatosis in MASLD: a lipid droplet perspective. [PDF]

J Clin Invest
Krahmer N, Walther TC, Farese RV.
europepmc   +1 more source

Cutaneous Lipogenesis IV. Role of the Pentose Phosphate Pathway During Lipogenesis in Guinea Pig Ear Skin

, 1973
Victor R. Wheatley, Mutukumara Kumarisiri, Joel Brind   +2 more
openalex   +1 more source

Defective uptake of triglyceride-associated fatty acids in adipose tissue causes the SREBP-1c-mediated induction of lipogenesis [PDF]

, 2004
Elke Wagner, Dagmar Kratky, Guenter Haemmerle, Andelko Hrzenjak, Gert M. Kostner, Ernst Steyrer, Rudolf Zechner   +6 more
openalex   +1 more source

Peptides From Adzuki Bean and Soybean Improved Insulin‐AKT Signaling‐Related Pathways in Healthy and Insulin‐Resistant States in Human Liver Cells

Molecular Nutrition &Food Research, EarlyView.
This study investigated the antidiabetic potential of adzuki bean β‐vignin and soybean β‐conglycinin peptides in human liver cells in healthy and insulin‐resistant states. Peptide Val‐Pro was found to inhibit dipeptidyl peptidase IV and stimulate the insulin signaling pathway, suggesting the potential for developing healthier adzuki bean‐based ...
Shu Hang Kwan, Elvira Gonzalez de Mejia
wiley   +1 more source

Hepatic Insulin Resistance and Steatosis in Metabolic Dysfunction-Associated Steatotic Liver Disease: New Insights into Mechanisms and Clinical Implications. [PDF]

Diabetes Metab J
Truong XT, Lee DH.
europepmc   +1 more source

Glucose‐Dependent Insulinotropic Polypeptide and Glucagon After Weight Loss Induced by Diet or Bariatric Surgery

Obesity, EarlyView.
ABSTRACT Objective This study compared the effects of a very low‐energy diet (VLED), alone or combined with sleeve gastrectomy (SG) or Roux‐en‐Y gastric bypass (RYGB), on glucose‐dependent insulinotropic polypeptide (GIP) and glucagon concentrations, hormones likely to play a role in weight loss maintenance.
Amanda Finn, Yenni Cedillo, Marthe Aukan, Barbara Gower, Catia Martins   +4 more
wiley   +1 more source

Adipose tissue-derived PRXL2A suppresses hepatic lipogenesis in a study with male mice. [PDF]

Nat Commun
Li Z, Tian Z, Shi X, Long A, Wang Y, Yang Y, Wang Y, Zhang J, Wang Y.   +8 more
europepmc   +1 more source

Expression of the Splicing Factor Gene SFRS10 Is Reduced in Human Obesity and Contributes to Enhanced Lipogenesis [PDF]

, 2011
Jussi Pihlajamäki, Carles Lerín, Paula Itkonen, Tanner Boes, Thomas Floß, Joshua Schroeder, Farrell Dearie, Sarah Crunkhorn, Furkan Burak, Josep C. Jiménez‐Chillarón, Tiina Kuulasmaa, Pekka Miettinen, Peter J. Park, Imad Nasser, Zhenwen Zhao, Zhaiyi Zhang, Yan Xu, Wolfgang Wurst, Hongmei Ren, Andrew J. Morris, Stefan Stamm, Allison B. Goldfine, Markku Laakso, Mary‐Elizabeth Patti   +23 more
openalex   +1 more source

Simultaneous Dual‐Color Stimulated Raman Scattering Biomolecular Imaging with Tailored Supercontinuum Generation and Phase‐Sensitive Detection

Small Methods, EarlyView.
A novel simultaneous dual‐color SRS (DC‐SRS) microscopy platform is developed by integrating tailored supercontinuum generation with phase‐sensitive detection, enabling simultaneous imaging of high‐wavenumber and cell‐silent Raman bands. This technique reveals subcellular metabolic activities and drug interactions in live cells and tumor spheroids ...
Le Xin, Zhiwei Huang
wiley   +1 more source