Results 191 to 200 of about 16,244 (260)

Association between dietary fatty acids and all‐cause mortality in patients with cirrhosis: A cohort study

open access: yesExperimental Physiology, EarlyView.
Abstract Liver cirrhosis imposes a substantial global burden, with complications driving high mortality. Diet is pivotal in managing liver disease progression and cirrhosis‐related death. This study investigated associations between total fat intake, specific dietary fatty acid subclasses and all‐cause mortality in cirrhotic patients.
Ali Jafari   +10 more
wiley   +1 more source

Maternal obesity during lactation as a hypertensive cardiovascular risk factor in the offspring

open access: yesExperimental Physiology, EarlyView.
Abstract Maternal obesity is a major public health concern, with growing evidence supporting its role in the developmental programming of cardiometabolic disease. Although prenatal mechanisms have been investigated extensively, the contribution of lactation as a postnatal window of cardiovascular (CV) programming remains insufficiently understood ...
Gabriela Arenas   +2 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu   +3 more
wiley   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

Mitochondrial permeability transition in skeletal muscle phenocopies muscle alterations seen in cancer cachexia and other wasting conditions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Skeletal muscle wasting conditions are characterized by muscle fibre atrophy, mitochondrial respiratory dysfunction, mitochondrial depletion and fragmentation of acetylcholine receptor (AChR) cluster at the neuromuscular junction.
Maya Semel   +10 more
wiley   +1 more source

Securing Long‐Chain Omega‐3 Fatty Acid Supply for Sustainable Aquaculture Development and Human Nutrition

open access: yesReviews in Aquaculture, Volume 19, Issue 1, January 2027.
Omega‐3 LC‐PUFA lie at the intersection of aquaculture performance and human nutrition. Deployment of w3 LC‐PUFA rich microalgal oils derived from low trophic levels offers credible long‐term sustainable solutions, taking full account of the potential environmental footprints and benefits in terms of human nutrition and health.
Sadasivam Kaushik, Douglas R. Tocher
wiley   +1 more source

Distinct Epigenetic Responses to Aging and Short‐Term High‐Fat Diet in Hepatic Lipid Metabolism Genes in Male and Female Mice

open access: yesLiver International Communications, Volume 7, Issue 4, December 2026.
ABSTRACT Background and Aims Aging is associated with widespread epigenetic remodelling that contributes to metabolic alterations in the liver. High‐fat diet (HFD) represents a major environmental perturbation affecting hepatic metabolism, yet its specific impact on age‐associated epigenetic changes remains unclear.
Annalena Frank   +10 more
wiley   +1 more source

Farnesoid X Receptor Agonist INT‐787 Protects Human Liver Organoids From Alcohol‐Induced Injury

open access: yesLiver International Communications, Volume 7, Issue 4, December 2026.
ABSTRACT Background Alcohol‐associated liver disease (ALD) represents a spectrum of liver injury ranging from steatosis to alcohol‐associated hepatitis, cirrhosis, and hepatocellular carcinoma. Activation of the farnesoid X receptor (FXR) decreases liver steatosis, inflammation, and fibrosis in animal models of liver‐related diseases, including ...
Francesca De Franco   +8 more
wiley   +1 more source

[Observations on lipogenesis].

open access: yesAnales de la Real Academia Nacional de Medicina, 2000
openaire   +1 more source

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