Results 231 to 240 of about 75,579 (341)

Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease.

Gastroenterology, 2014
Jennifer E Lambert, M. Ramos-Roman, J. Browning, E. Parks   +3 more
semanticscholar   +1 more source

Endocrine Disorders and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Narrative Review. [PDF]

Biomedicines
Betlejewska J, Hubska J, Roszkowska Z, Maciejczyk A, Bachurska D, Domański J, Miarka M, Raszeja-Wyszomirska J, Bobrowicz M, Ambroziak U.   +9 more
europepmc   +1 more source

Multi‐pathway‐driven hepatic protection: Semaglutide combined with HIIT counteracts diabetic liver injury in db/db mice

Journal of Diabetes Investigation, EarlyView.
This study reveals that the new drug semaglutide combined with high‐intensity interval training is significantly better than a single drug in improving liver metabolic abnormalities in type 2 diabetes. Untargeted metabolomics studies showed that the synergistic effect was mainly achieved by regulating key pathways such as the TCA cycle, amino acid ...
Wenjun Yu, Yongfu Liu, Shenglong Le, Yuxin Xiao, Xiaoyan Chen, Junhua Wang, Feng Gao   +6 more
wiley   +1 more source

Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways

, 2008
Keun‐Gyu Park, Ae-Kyung Min, Eun Hee Koh, Hyoun Sik Kim, Mi‐Ok Kim, Hye‐Sun Park, Yong-Deuk Kim, Tae-Seung Yoon, Byoung Kuk Jang, Jae Seok Hwang, Jae Bum Kim, Hueng-Sik Choi, Joong‐Yeol Park, In‐Kyu Lee, Ki‐Up Lee   +14 more
openalex   +2 more sources

Metabolic Heterogeneity Confers Differences in the Tumor Microenvironment of Aggressive Types of Melanomas

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Melanoma affects skin and mucosa and can be particularly aggressive when the lesion is an advanced cutaneous tumor or located in the sinonasal or oral mucosa. Reprogramming of energy metabolism has been defined as a hallmark of cancer; so this study aimed to verify the expression of proteins related to metabolism and cellular ...
Juliana de Souza do Nascimento, João Figueira Scarini, Erika Said Abu Egal, Marcelo Brum Corrêa, Rodrigo Ribas Dias dos Reis, Luciana Schultz Amorim, Rachel Martins Marinho Robim, Clóvis Antônio Lopes Pinto, Patricia Maria Peresi, Ana Lucia Noronha Francisco, Felipe Paiva Fonseca, Luiz Paulo Kowalski, Román Carlos, Fernanda Viviane Mariano, Albina Altemani   +14 more
wiley   +1 more source

Effect of (Poly)phenols on Lipid and Glucose Metabolisms in 3T3-L1 Adipocytes: an Integrated Analysis of Mechanistic Approaches. [PDF]

Curr Obes Rep
Rendine M, Marino M, Martini D, Riso P, Møller P, Del Bo' C.   +5 more
europepmc   +1 more source

Smad4 deficiency in hepatocytes attenuates NAFLD progression via inhibition of lipogenesis and macrophage polarization

Wei Yang, Xuanxuan Yan, Rui Chen, Xin Xin, Shuang Ge, Yongxiang Zhao, Xinlong Yan, Jinhua Zhang   +7 more
openalex   +1 more source

Dietary Phosphorus Requirement for Tambaqui, Colossoma macropomum, in the Grow‐Out Phase

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Phosphorus is essential for fish growth as it is crucial in skeletal development and metabolic reactions. The dietary requirement for this mineral varies among fish species and growth stages. Therefore, the objective of this study was to determine the available phosphorus (AP) requirement for tambaqui during the grow‐out phase (± 400 to 1000 g)
Ludmila L. C. Menezes, Vânia M. Machado, Cristielle N. Souto, Danilo C. Proença, Guilherme W. Bueno, Igo G. Guimarães   +5 more
wiley   +1 more source

USP24 upregulation stabilizes PKA-Cα to promote lipogenesis, inflammation, and fibrosis during MASH progression. [PDF]

J Biomed Sci
Ning B, Wang SA, Young MJ, Chen YC, Hung Y, Huong TT, Chang WC, Wang YC, Yu ML, Hsu KC, Hung JJ.   +10 more
europepmc   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source