Results 241 to 250 of about 102,476 (312)

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

Targeting SREBP-dependent lipogenesis potentiates the anti-tumor activity of docetaxel by increasing membrane permeability and intracellular drug accumulation. [PDF]

Oncogene
Chen J, Wang ME, Bawcom AR, Lu Y, Asara JM, Li L, Chen M.   +6 more
europepmc   +1 more source

Gastric Cancer: Pathobiology and Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
Gastric cancer is a multistep process driven by the interplay of microbial virulence, host epithelial injury, and evolving molecular reprogramming. Initiation involves pathogen‐induced epigenetic alterations and the early subversion of key oncogenic signaling networks, facilitating the transition from chronic injury to metaplasia and malignant ...
Ruixian Yu, Miao Zhang, Yan Meng, Chunxiao Zhu, Weihong Zhang, Hui Zhang, Zhifa Cao, Meihang Du, Zhangting Zhao, Junping Bai, Yi Han, Yang Tang, Wei Kang, Ka Fai To, Shi Jiao, Liwei An, Zhaocai Zhou   +16 more
wiley   +1 more source

Synergistic therapeutic strategies for metabolic dysfunction-associated steatohepatitis and type 2 diabetes mellitus: molecular insights and clinical advances. [PDF]

Front Endocrinol (Lausanne)
Zhu B.
europepmc   +1 more source

Microalgae and Cyanobacteria in the Obesity Evidence Landscape: A PRISMA-ScR Scoping Review with Mechanistic and Safety Mapping. [PDF]

Biology (Basel)
Huynh QP, Quan QD, Ho VT, Le QT, Nguyen HC, Tran HD.   +5 more
europepmc   +1 more source

Polyphenol-rich Chinese olive extracts attenuate lipid accumulation in HepG2 cells, accompanied by AMPK phosphorylation and miRNA alterations. [PDF]

Front Nutr
Wang H, Huang B, Zhao W, Liu G, Bai W.
europepmc   +1 more source

Lipid Metabolism-Signaling Crosstalk in Metabolic Disease and Aging: Mechanisms and Therapeutic Targets. [PDF]

Nutrients
Sethi P, Mishra AK, Ghosh S, Singh KK, Sharma S, Stojchevski R, Avtanski D, Sinha JK.   +7 more
europepmc   +1 more source

Stable Isotopes for the Study of Energy Nutrient Metabolic Pathways in Relation to Health and Disease. [PDF]

Metabolites
Azzout-Marniche D, Tomé D.
europepmc   +1 more source

ACSL3 Promotes Hepatocellular Carcinoma Tumorigenesis and Correlates With JAK-STAT3 Signaling. [PDF]

Cancer Med
Amelimojarad M, Amelimojarad M, Pourmahdian A, Lu Z.   +3 more
europepmc   +1 more source