Results 231 to 240 of about 102,476 (312)

Elevated Kallistatin Induces Myosteatosis and Exercise Intolerance by Antagonizing AdipoR1-Mediated AMPK Signalling. [PDF]

J Cachexia Sarcopenia Muscle
Hong F, Fang Z, Shen G, Wang Y, Li Y, Zhong Y, Dai J, Zhang C, Zhang J, Chen W, Qi W, Yang X, Gao G, Zhou T.   +13 more
europepmc   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Cannabidiolic acid as a modulator of lipid metabolism in the liver of rats with metabolic-associated steatotic liver disease. [PDF]

Sci Rep
Kurzyna PF, Chabowski P, Zwierz M, Harasim-Symbor E, Dzięcioł J, Klimek J, Ryszkiewicz P, Chabowski A, Konstantynowicz-Nowicka K.   +8 more
europepmc   +1 more source

Equol Alleviates Postmenopausal Metabolic Dysfunction‐Associated Steatotic Liver Disease via the GPR30/PI3K Pathway

eFood, Volume 7, Issue 3, June 2026.
This study demonstrates that equol exerts a protective effect on metabolic dysfunction‐associated steatotic liver disease in both in vivo and in vitro by activating the GPR30/PI3K/Nrf2 signaling pathway. Equol's interaction with GPR30 and its ability to activate the PI3K/Nrf2 pathway provide a promising therapeutic strategy for treating metabolic ...
Hanqiang Cui, Bin Wang, Bo Zou, Guiming Zhang, Zhe Xu, Shuo Li, Jing Xu, Xiangmin Ni, Jian Wang   +8 more
wiley   +1 more source

DDR2 ameliorates nonalcoholic hepatic steatosis by activating the AMPK/ACC pathway. [PDF]

Sci Rep
Guo M, Lin L, Wang Y, Gao J, Wei X, Hua H, Wang D, Huang C, Wang X, Zou B, Zhang L, Zhang H, Chen Q.   +12 more
europepmc   +1 more source

Targeting Cancer Cachexia: A Mechanistic Evaluation of Anti‐GDF‐15 Antibody‐Based Combination Therapies

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background In a recent Phase 2 trial in patients with cancer cachexia, the anti‐GDF‐15 antibody ponsegromab resulted in increased body weight, appetite, muscle mass and physical activity. This study provides compelling evidence that targeting the GDF‐15 pathway may offer a viable therapeutic strategy, while raising new mechanistic questions ...
Danna M. Breen, Stephanie Joaquim, Brianna LaCarubba Paulhus, Donald Bennett, Barbara Bernardo, Susie Collins, Ryan M. Esquejo, Ja Young Kim‐Muller, Laura Lin, Matthew Peloquin, Zhidan Wu, Shuxi Qiao, John C. Stansfield, Bei B. Zhang, Michelle I. Rossulek   +14 more
wiley   +1 more source

Ferulic acid inhibits lipogenesis and ameliorates MASLD via targeting PGC-1β. [PDF]

Front Nutr
Cui K, Ren L, Zhang L, An Y, Ji P, Yang Y, Li F, Li Z.   +7 more
europepmc   +1 more source

Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application

MedComm, Volume 7, Issue 6, June 2026.
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang, Runkang Zhao, Fan Zhang, Dandan Guo, Qing Li, Zhijun Shen, Ruiqing Gao, Chenyu Gao, Zhao Xie, Sentao Fu, Peng Luo, Bufu Tang, Ling Wang   +12 more
wiley   +1 more source

Targeting the LPI/GPR55 Axis in MAFLD and MASH: Novel Insights, Therapeutic Strategies and Future Directions. [PDF]

Liver Int
Lian J, Lareu RR, Patil M, Falasca M.
europepmc   +1 more source

[Observations on lipogenesis].

Anales de la Real Academia Nacional de Medicina, 2000
openaire   +1 more source