Unraveling the complexities of diet induced obesity and glucolipid dysfunction in metabolic syndrome. [PDF]
Diabetol Metab SyndrDutta B +3 more
europepmc +1 more source
Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle
Experimental Physiology, EarlyView.Abstract MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an acute exercise bout, its association with metabolic disorders, and the effects of ...
Natália Pálešová +10 more
wiley +1 more source
Childhood insulin resistance and neural stem cell dysfunction in psychiatric disorders: Role of <i>de novo</i> lipogenesis and treatment perspectives. [PDF]
World J Stem CellsKhan MM, Khan ZA, Khan MA, Pandey G.
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend This graphical abstract is a schematic representation highlighting the interactions between dietary fructose, gut microbiota and ethnicity in shaping metabolic health. Abstract Important health disparities are observed in the prevalence of obesity and associated non‐communicable diseases (NCDs), including type 2 diabetes (T2D ...
Florine H.M. Westerbeke +3 more
wiley +1 more source
SREBP1-Dependent Metabolism as a Potential Target for Breast Cancer Risk Reduction. [PDF]
Cancers (Basel)Hajirahimkhan A +3 more
europepmc +1 more source
Protocol for a randomized placebo-controlled clinical trial using pure palmitoleic acid to ameliorate insulin resistance and lipogenesis in overweight and obese subjects with prediabetes [PDF]
Ecesu Çetin +4 more
openalex +1 more source
Oxyntomodulin physiology and its therapeutic development in obesity and associated complications
The Journal of Physiology, EarlyView.Abstract figure legend Physiological influences of OXM and its emerging insights from evidence on bariatric surgery effects. CCK, cholecystokinin; FGF21, fibroblast growth factor 21; GLUT4, glucose transporter type 4; IRS1, insulin receptor substrate‐1; NNMT, nicotinamide N‐methyltransferase; OXM, oxyntomodulin Abstract Incretins, such as glucagon‐like
Martin T. W. Kueh +3 more
wiley +1 more source
Anti-Obesity Effects of <i>Rosa rugosa</i> Thunb. Flower Bud Extracts on Lipid Metabolism Regulation in 3T3-L1 Adipocytes and Sprague Dawley Rats. [PDF]
Int J Mol SciKim JM, Kim KK, Lee HR, Im JC, Kim TW.
europepmc +1 more source
Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation
The Journal of Physiology, EarlyView.Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson +7 more
wiley +1 more source