Results 271 to 280 of about 77,919 (340)

Ellagic Acid Alleviates Abnormal Fat Reduction by Activating the RXRβ–PPARγ Pathways in a CT26 Tumour‐Induced Cachexia Mouse Model

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Cancer cachexia is a syndrome characterized by significant weight loss, particularly of adipose tissue, which negatively impacts patient survival. Pharmacological approaches to prevent this abnormal fat reduction remain poorly defined.
Woo Yong Park, Beomsu Kim, Gahee Song, Sang Hee Kim, Jin‐Hyung Kim, Ja Yeon Park, Se Jin Jung, Wenjun Jiao, Jisoo Han, Taekyoung Kong, Kwang Seok Ahn, Hyun Jeong Kwak, Jae‐Young Um   +12 more
wiley   +1 more source

Maternal western-style diet alters Kupffer cell proportion leading to metabolic dysfunction-associated steatotic liver disease when challenged with western diet in adulthood. [PDF]

Front Immunol
Miller SJ, Janssen RC, Zhao W, Jonscher KR, Zhong H, DeVette CI, Friedman JE, Zimmerman KA.   +7 more
europepmc   +1 more source

Bile Acid Binding Resins Improve Glucagon Receptor Agonist‐Mediated Weight Loss in Diet‐Induced Obese Mice

Obesity, Volume 34, Issue 2, Page 428-438, February 2026.
ABSTRACT Objective Glucagon‐receptor (GCGR) agonism reguglates bile acid (BA) metabolism and promotes weight loss in diet‐induced obese (DIO) mice. Thus, we hypothesized that BA signaling contributes to GCGR‐stimulated weight loss. Methods To test this hypothesis, we utilized BA‐binding resins (BARs; colesevelam [Colsv] and cholestyramine [Cstyr]) to ...
Teayoun Kim, Mackenzie J. Pearson, Huixian Hong, Shelly Nason, Khadija Seck, Jessica Antipenko, Natalie Presedo, Richard DiMarchi, William C. Roell, Kirk Habegger   +9 more
wiley   +1 more source

Adipose tissue-derived PRXL2A suppresses hepatic lipogenesis in a study with male mice. [PDF]

Nat Commun
Li Z, Tian Z, Shi X, Long A, Wang Y, Yang Y, Wang Y, Zhang J, Wang Y.   +8 more
europepmc   +1 more source

Yeast‐Based Biotechnology for Civilian Security

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Yeasts constitute robust and versatile eukaryotic platforms for biotechnological applications relevant to civilian security. Both native and genetically engineered yeast systems enable sensitive detection of chemical and biological hazards, effective removal of metals and organic pollutants, and detoxification of mycotoxins.
Justyna Ruchała, Roksolana Vasylyshyn, Maciej Wnuk   +2 more
wiley   +1 more source

The role of natural compounds in modulation of small extracellular vesicle biogenesis and lipid metabolism in cancer. [PDF]

Front Mol Biosci
Lim GY, Santhakumar L, Mielczarek-Puta M, Skrzycki M.   +3 more
europepmc   +1 more source

Acyl‐CoA Binding Protein in White and Brown Adipose Tissue Is Dispensable for Systemic Energy Metabolism in Mice

Acta Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Aim Acyl‐CoA binding protein plays a vital role in lipid metabolism by mediating the intracellular flux and utilization of long‐chain acyl‐CoAs. We generated an adipocyte‐wide ACBP knockout mouse and a brown adipose tissue‐specific ACBP knockout mouse to investigate ACBP function in adipose tissue.
M. F. Nørremark, R. Petersen, P. M. M. Ruppert, E. S. Jul, T. K. Doktor, R. Nielsen, J. F. Kappel, S. Larsen, J. W. Kornfeld, S. Mandrup, B. S. Andresen, J. Havelund, D. Neess, N. J. Færgeman   +13 more
wiley   +1 more source

Nutritional intervention with perennial ryegrass alleviates hepatic dysfunction by modulating lipid metabolism: insights from gut-liver axis. [PDF]

Poult Sci
Asif MA, Zulfiqar Z, Mustafa BE, Saif S, Wang Z, Cui Y, Hao S, Boshuai L, Shi Y.   +8 more
europepmc   +1 more source

Effects of hypoxic training interventions on cardiometabolic health of adults with overweight and obesity: A systematic review and meta‐analysis

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 865-877, February 2026.
Abstract Obesity rates have surpassed underweight globally, increasing the burden of cardiometabolic complications on healthcare systems. Hypoxic training has emerged as a potential intervention to improve cardiometabolic health in adults with obesity, but evidence remains inconclusive. This systematic review and meta‐analysis evaluated whether hypoxic
Alessandro Gatti, Caterina Cavallo, Matteo Giuriato, Agnese Pirazzi, Vittoria Carnevale Pellino, Nicola Lovecchio, Stefano Lazzer, Virginia Rossi, Valeria Calcaterra, Gianvincenzo Zuccotti, Anna Odone, Alba Camacho‐Cardenosa, Matteo Vandoni   +12 more
wiley   +1 more source

Heart matters: How glucose‐ and lipid‐modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 878-894, February 2026.
Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck, Charnkamal Singh Bhogal, Markus Mandl   +2 more
wiley   +1 more source