Results 301 to 310 of about 75,579 (341)

Anti‐acne vulgaris effects of chlorogenic acid by anti‐inflammatory activity and lipogenesis inhibition

Experimental Dermatology, 2021
Chlorogenic acid (CGA) exhibits substantial biological function in antioxidant, antibacterial, anti‐lipogenesis and anti‐inflammatory activities. Increased sebum production and inflammation are considered important for the development of acne.
Jiao Luo, Weiyi He, Xuan Li, Xunmin Ji, Jiabang Liu   +4 more
semanticscholar   +1 more source

Hepatic glycogenesis antagonizes lipogenesis by blocking S1P via UDPG

Science
The identification of mechanisms to store glucose carbon in the form of glycogen rather than fat in hepatocytes has important implications for the prevention of nonalcoholic fatty liver disease (NAFLD) and other chronic metabolic diseases.
Jie Chen, Yabo Zhou, Zhuohang Liu, Yan Lu, Yishen Jiang, Kexin Cao, Nannan Zhou, Dianheng Wang, Chaoqi Zhang, Ning Zhou, K. Shi, Lu Zhang, Li Zhou, Zhenfeng Wang, Huafeng Zhang, Ke Tang, Jingwei Ma, Jiadi Lv, Bo Huang   +18 more
semanticscholar   +1 more source

Lipogenesis in biotin deficiency

Canadian Journal of Biochemistry, 1968
The effect of biotin deficiency on the lipid composition of rat liver, epididymal fat pad, and carcass was investigated. The incorporation of acetate-1-14C into liver lipids, the concentration of liver acetyl-CoA, and the in vitro activities of mitochondrial and supernatant pathways were also studied in biotin-deficient and pair-weighed controls ...
K. Dakshinamurti, P. R. Desjardins
openaire   +3 more sources

Fatty Acid Synthase Inhibitor TVB‐2640 Reduces Hepatic de Novo Lipogenesis in Males With Metabolic Abnormalities

Hepatology, 2020
Elevated hepatic de novo lipogenesis (DNL) is a key distinguishing characteristic of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis.
M. M. Syed-Abdul, E. Parks, Ayman H. Gaballah, Kimberlee Bingham, G. Hammoud, G. Kemble, D. Buckley, W. McCulloch, Camila Manrique-Acevedo   +8 more
semanticscholar   +1 more source

Inhibition of Lipogenesis by pycnogenol

Phytotherapy Research, 2000
The influence of pycnogenol on the adipose conversion of 3T3-L1 cells by insulin was studied. In week 3 of culture with insulin, pycnogenol was found to inhibit significantly the expression of glycerophosphate dehydrogenase (p < 0.01). This finding suggests that pycnogenol inhibits the accumulation of lipid droplets in adipose tissue.
openaire   +3 more sources

Androgen Regulation of Lipogenesis

2002
In several tissues and cell lines, including epithelial cells of the prostate, breast and seminal vesicles, and in acinar cells of the meibomian and other sebaceous glands, androgens have a major stimulatory effect on the production, accumulation and/or secretion of lipids.1–11 In most of these tissues and cell lines, the composition of these lipids is
Johannes V. Swinnen, Hannelore Heemers, Guido Verhoeven, Walter Heyns   +3 more
openaire   +2 more sources

Inhibitory mechanisms in the control of lipogenesis

Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects, 1963
Synthesis of fatty acids by supernatant prepared from livers of fed rats was measured when various cytoplasmic particles of livers from fed or fasted rats were present. Microsomal inhibition of lipogenesis occurs at the acetyl-CoA carboxylase (acetyl-CoA:CO2 ligase (ADP), EC 6.4.1.2) step and involves at least two mechanisms: The action of a microsomal
H.M. Korchak, E. J. Masoro
openaire   +3 more sources

Lipogenesis in an adult parasitic wasp

Journal of Insect Physiology, 2003
The goal of this study was to determine the extent of lipogenesis in the parasitoid Eupelmus vuilletti (Hymenoptera: Eupelmidae). Carbohydrate and lipid metabolism were followed in glucose-fed and starved females over 3 days. Fed females increased their glycogen level, while maintaining their lipid level.
Jérôme Casas, David Giron
openaire   +3 more sources

Regulatory function of mitochondria in lipogenesis [PDF]

Lipids, 1973
AbstractA cell‐free system, consisting of particle‐free rat liver cytoplasm plus purified mitochondria, was used to study the synthesis of fatty acid from14C‐U‐alanine. Incorporation of label into lipid was dependent upon the presence of both cytoplasm and mitochondria.
Michael C. Leland, J. P. Mapes, Robert A. Harris, Joan Munroe Mahoney   +3 more
openaire   +2 more sources

LIPOGENESIS IN DIABETES AND OBESITY

Nutrition Reviews, 2009
Non-insulin-dependent diabetes mellitus did not affect de novo fatty acid synthesis by hepatocytes from fasted obese subjects.
openaire   +2 more sources