Results 301 to 310 of about 77,919 (340)

Lipogenesis in biotin deficiency

Canadian Journal of Biochemistry, 1968
The effect of biotin deficiency on the lipid composition of rat liver, epididymal fat pad, and carcass was investigated. The incorporation of acetate-1-14C into liver lipids, the concentration of liver acetyl-CoA, and the in vitro activities of mitochondrial and supernatant pathways were also studied in biotin-deficient and pair-weighed controls ...
K, Dakshinamurti, P R, Desjardins
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Hepatic glycogenesis antagonizes lipogenesis by blocking S1P via UDPG

Science
The identification of mechanisms to store glucose carbon in the form of glycogen rather than fat in hepatocytes has important implications for the prevention of nonalcoholic fatty liver disease (NAFLD) and other chronic metabolic diseases.
Jie Chen, Yabo Zhou, Zhuohang Liu, Yan Lu, Yishen Jiang, Kexin Cao, Nannan Zhou, Dianheng Wang, Chaoqi Zhang, Ning Zhou, K. Shi, Lu Zhang, Li Zhou, Zhenfeng Wang, Huafeng Zhang, Ke Tang, Jingwei Ma, Jiadi Lv, Bo Huang   +18 more
semanticscholar   +1 more source

Fatty Acid Synthase Inhibitor TVB‐2640 Reduces Hepatic de Novo Lipogenesis in Males With Metabolic Abnormalities

Hepatology, 2020
Elevated hepatic de novo lipogenesis (DNL) is a key distinguishing characteristic of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis.
M. M. Syed-Abdul, E. Parks, Ayman H. Gaballah, Kimberlee Bingham, G. Hammoud, G. Kemble, D. Buckley, W. McCulloch, Camila Manrique-Acevedo   +8 more
semanticscholar   +1 more source

Androgen Regulation of Lipogenesis

2002
In several tissues and cell lines, including epithelial cells of the prostate, breast and seminal vesicles, and in acinar cells of the meibomian and other sebaceous glands, androgens have a major stimulatory effect on the production, accumulation and/or secretion of lipids.1–11 In most of these tissues and cell lines, the composition of these lipids is
Johannes V, Swinnen, Hannelore, Heemers, Walter, Heyns, Guido, Verhoeven   +3 more
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The IKKβ‐USP30‐ACLY Axis Controls Lipogenesis and Tumorigenesis

Hepatology, 2020
Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death that develops as a consequence of obesity, cirrhosis, and chronic hepatitis. However, the pathways along which these changes occur remain incompletely understood.
Li Gu, Yahui Zhu, Xi Lin, Bingjun Lu, Xinyi Zhou, Feng Zhou, Qiu Zhao, E. Prochownik, Youjun Li   +8 more
semanticscholar   +1 more source

Experimental Aberrant Lipogenesis

A.M.A. Archives of Ophthalmology, 1959
Aberrant lipogenesis is a phenomenon which has been described by Cogan and Kuwabara in the first four articles of the present series. 1-4 The term "aberrant lipogenesis" refers to the formation of fat by tissues or cells which do not ordinarily form fat.
openaire   +2 more sources

Fat mass and obesity‐associated protein regulates lipogenesis via m6A modification in fatty acid synthase mRNA

Cell Biology International, 2020
As the first identified N6‐methyladenosine (m6A) demethylase, fat mass and obesity‐associated (FTO) protein is associated with fatty acid synthase (FASN) and lipid accumulation.
Donglei Sun, Tianhe Zhao, Qian Zhang, Mei Wu, Zunzhen Zhang   +4 more
semanticscholar   +1 more source

Androgens, lipogenesis and prostate cancer

The Journal of Steroid Biochemistry and Molecular Biology, 2004
Both experimental and epidemiological data indicate that androgens are among the main factors controlling the development, maintenance and progression of prostate cancer. Identifying the genes that are regulated by androgens represents a major step towards the elucidation of the mechanisms underlying the impact of androgens on prostate cancer cell ...
Johannes V, Swinnen, Hannelore, Heemers, Tine, van de Sande, Ellen, de Schrijver, Koen, Brusselmans, Walter, Heyns, Guido, Verhoeven   +6 more
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Physiological and pathological roles of lipogenesis

Nature Metabolism, 2023
Yong Geun Jeon, Y. Kim, Gung Lee, Jae Bum Kim   +3 more
semanticscholar   +1 more source

Lipogenesis in rat tissues following carbohydrate refeeding: Spleen lipogenesis is modulated by insulin

Molecular and Cellular Biochemistry, 1997
Intraperitoneal administration of [1,2-14C]-acetate to Wistar rats was used to assess tissue lipogenic rates after estimating the incorporation of the label into the tissular lipid fractions. Refeeding the animals with glucose (after an overnight fast) induced an increase in white adipose tissue (4.5 fold), liver (4.1 fold), small intestine (1.9 fold),
M, Hulstijn, J, López-Soriano, F J, López-Soriano, J M, Argilés   +3 more
openaire   +2 more sources