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Inhibition of Lipogenesis by pycnogenol
Phytotherapy Research, 2000The influence of pycnogenol on the adipose conversion of 3T3-L1 cells by insulin was studied. In week 3 of culture with insulin, pycnogenol was found to inhibit significantly the expression of glycerophosphate dehydrogenase (p < 0.01). This finding suggests that pycnogenol inhibits the accumulation of lipid droplets in adipose tissue.
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LIPOGENESIS IN DIABETES AND OBESITY
Nutrition Reviews, 2009Non-insulin-dependent diabetes mellitus did not affect de novo fatty acid synthesis by hepatocytes from fasted obese subjects.
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Chemical genetics in tumor lipogenesis
Biotechnology Advances, 2018Since cancer cells depend on de novo lipogenesis for energy supply, highly active membrane biosynthesis and signaling, enhanced fatty acid synthesis is a crucial characteristic of cancer cells. Hence, targeting lipogenic enzymes and signaling cascades is a very promising approach in developing innovative therapeutic agents for the fight against cancer.
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Hormonal Control of Hepatic Lipogenesis
1979Hepatic lipogenesis is subject to both fine (short-term) and coarse (long-term) control mechanisms. Coarse control, i.e., adaptive change in enzyme quantity, is recognized as being important for nutritional and hormonal control of lipogenesis (for reviews see Gibson, Lyons, Scott, and Muto, 1972; Goodridge, 1975; Lakshmanan, Nepokroeff, and Porter ...
R A, Harris +4 more
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Epidermal Lipogenesis in Ichthyosis
1978Several lines of evidence point to a connection between lipid metabolism and scaly skin. Inhibitors of cholesterol biosynthesis such as triparanol and nicotinic acid can produce scaly lesions superficially resembling ichthyosis1. A disturbance of cutaneous sterol ester biosynthesis accompanies the hyperkeratosis of essential fatty acid deficiency2, and
Mary F. Cooper, D. McGibbon, S. Shuster
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The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis
Nature, 2020Daqian Xu +17 more
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Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1973
Leonard T. Hodgins, Victor R. Wheatley
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Leonard T. Hodgins, Victor R. Wheatley
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Lipogenesis Pathway: Radiolabeled Choline
2019The radiolabeled choline is a PET/CT radiopharmaceutical useful in detecting tumors with high lipogenesis rate.
Ferdinando Calabria +3 more
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