Results 301 to 310 of about 123,419 (342)

Droplet Size Reduction of Self-Emulsifying Drug Delivery System (SEDDS) Using the Hybrid of Medium and Long-Chain Triglycerides. [PDF]

Pharmaceutics
Qian K, Lin Y, Zhao B, Liu X.
europepmc   +1 more source

Circadian Clock: A Regulator of Immunity in Autoimmune Diseases

Immunity, Inflammation and Disease, Volume 13, Issue 9, September 2025.
This review explores the intricate connections between circadian clocks and immune responses in autoimmune diseases. We aim to open new avenues for therapeutic interventions, including chronotherapy and targeting clock genes, with the potential to improve treatment outcomes in autoimmune diseases.
Ye‐Jun Wu, Shu‐Ying Zhang, Hong‐Yu Chen, Xin‐Ran He, Guang‐Rui Yang   +4 more
wiley   +1 more source

High intensity interval training attenuate insulin resistance in diabetic rats accompanied by improvements in liver metabolism and spexin signaling. [PDF]

Sci Rep
Khoramipour K, Hosseini NS, Hill JW, Khoramipour K, Khoramipour K, Izquierdo SM, Lista S, Saheli M.   +7 more
europepmc   +1 more source

Lipid‐Based Nanoplatforms in Hepatology: From Rational Design to Clinical Translation Challenges

MedComm – Biomaterials and Applications, Volume 4, Issue 3, September 2025.
The recent advances in the rational design and application of lipid‐based nanocarriers and materials in hepatic disorders are summarized, including liposomes, micelles, nanoemulsions, solid lipid nanoparticles, nanostructured lipid carriers, lipid nanoparticles, biomimetic lipid nanocarriers, and smart responsive lipid nanocarriers.
Jie Wang, Qian Zhang, Lin Yang, Zijian Cheng, Chunhong Wang, Runlin Song, Honglan Dai, Xinxin Zhang   +7 more
wiley   +1 more source

Plin5: A potential therapeutic target for type 2 diabetes mellitus. [PDF]

Diabetol Metab Syndr
Wei M, Wang Y, Zhang Y, Qiao Y.
europepmc   +1 more source

LJ-1888, a selective antagonist for the A3 adenosine receptor, ameliorates the development of atherosclerosis and hypercholesterolemia in apolipoprotein E knock-out mice [PDF]

, 2018
Jeong, Lak Shin, Jeong, Se-Jin, Kim, Gyudong, Oh, Goo Taeg, Park, Jong-Gil, Yu, Jinha   +5 more
core   +1 more source

Mitochondrial Dysfunction in Neurodegenerative Diseases

MedComm, Volume 6, Issue 9, September 2025.
Overview of mitochondrial dysfunction in neurodegenerative diseases (NDDs). Mitochondrial dysfunction in NDDs involves impaired ATP synthesis, Ca2+ imbalance, oxidative stress, and apoptosis. Assessment methods integrate functional assays, omics, and imaging.
Chongyang Chen, Yujie Zhao, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Xifei Yang, Ming Lu, Gong‐Ping Liu   +10 more
wiley   +1 more source

Adipocyte-derived shed Syndecan-4 suppresses lipolysis contributing to impaired adipose tissue browning and adaptive thermogenesis. [PDF]

Mol Metab
Zong J, Wu X, Huang X, Yuan L, Yuan K, Zhang Z, Jiang M, Ping Z, Cheong LY, Xu A, Hoo RLC.   +10 more
europepmc   +1 more source

Polarization of Tumor Cells and Tumor‐Associated Macrophages: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 6, Issue 9, September 2025.
Bidirectional metabolic interactions between tumor cells and TAMs in the TME metabolic reprogramming facilitates reciprocal crosstalk between TAMs and tumor cells within the immunosuppressive TME. This interaction promotes both the pro‐tumor functions of TAMs and tumor mesenchymal transition through complex molecular signaling.
Guohao Wei, Bin Li, Mengyang Huang, Mengyao Lv, Zihui Liang, Chuandong Zhu, Lilin Ge, Jing Chen   +7 more
wiley   +1 more source

Disrupting lipid homeostasis with CAV2 in OSCC triggers apoptosis, lipolysis, and mitochondrial dysfunction by transcriptional repression of PPARγ. [PDF]

Cell Biosci
Bai Y, Jiang M, Chen X, Zhou G.
europepmc   +1 more source