Results 121 to 130 of about 24,712 (234)

Optimization transgene expression of short fully synthesized lipopeptide-based transfection agent for non-viral gene delivery vehicle [PDF]

, 2018
Gene therapy using non-viral gene delivery vehicle might be applied for the treatment of viral infection, cancer and genetic disorders. However, the most challenging barrier is the low efficiency of transgene expression.
Kartasasmita, Rahmana E., Restiani, Dewi E., Pambudi, Sabar, H Rachmawati (18836893), RE Kartasasmita (18836896), S Pambudi (18836887), Jazayeri, Jalal J., DE Restiani (18836884), Jalal J Jazayeri (18836890), Asyarie, Sukmadjaja, Tarwadi (18836881), Pouton, Colin W., Rachmawati, Heni, Tarwadi, S Asyarie (18836899), CW Pouton (15979460)   +15 more
core  

A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor

Pharmacological Research
β-arrestins play pivotal roles in seven transmembrane receptor (7TMR) signalling and trafficking. To study their functional role in regulating specific receptor systems, current research relies mainly on genetic tools, as few pharmacological options are ...
Rebecca L. Brouillette, Christine E. Mona, Michael Desgagné, Malihe Hassanzedeh, Émile Breault, Frédérique Lussier, Karine Belleville, Jean-Michel Longpré, Michel Grandbois, Pierre-Luc Boudreault, Élie Besserer-Offroy, Philippe Sarret   +11 more
doaj   +1 more source

Formation and characterization of lipopeptide layers at interfaces for the molecular recognition of antibodies [PDF]

A lipopeptide, carrying the antigenic peptide segment 135-154 of VP1, one of the capsid proteins of the picornavirus which causes foot-and-mouth disease in cattle, was investigated in lipid monolayers on the water surface and on hydrophobic solid ...
Duschl, Claus, Boncheva, Mila, Vogel, Horst, Beck, Werner, Jung, Guenter   +4 more
core   +1 more source

Supramolecular Complexes of Ultrashort Cationic Lipopeptides with Cyclodextrins: Improved Selectivity and Therapeutic Potential

Aggregate
In the last decade, the rise of antibiotic resistance has heightened interest in antimicrobial peptides and lipopeptides as promising alternatives to conventional antibiotics because of their lower propensity to develop resistance.
Chiara Bellini, Unai Atxabal, Szilvia Bősze, Orsolya Dobay, Andrea Horváth, Imola Cs. Szigyártó, Tamás Beke‐Somfai, Jesús Jiménez‐Barbero, István Puskás, Kata Horváti   +9 more
doaj   +1 more source

Potential Use of Microbial Surfactant in Microemulsion Drug Delivery System: A Systematic Review

Drug Design, Development and Therapy, 2020
Mandana Ohadi,1 Arash Shahravan,2 Negar Dehghannoudeh,3 Touba Eslaminejad,1 Ibrahim M Banat,4 Gholamreza Dehghannoudeh1,5 1Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran; 2Endodontology ...
Ohadi M, Shahravan A, Dehghannoudeh N, Eslaminejad T, Banat IM, Dehghannoudeh G   +5 more
doaj  

Development of potent pan‐coronavirus fusion inhibitors with a new design strategy

MedComm
Development of potent and broad‐spectrum drugs against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) remains one of the top priorities, especially in the cases of the emergence of mutant viruses and inability of current vaccines to prevent
Yuanmei Zhu, Zhongcai Gao, Xiaoli Feng, Lin Cheng, Nian Liu, Chao Liu, Shaowei Han, Qiaojiang Yang, Qingcui Zou, Huihui Chong, Zheng Zhang, Minghua Li, Gengshen Song, Yuxian He   +13 more
doaj   +1 more source

Experiments, Modeling, and Media Optimization of Rhamnolipid and Lipopeptide Production [PDF]

, 2016
Biosurfactants\ud are\ud attractive alternative\ud s\ud to synthetic surfactants due to their \ud environment\ud -\ud friendly nature and wide applications. The most important limitations \ud for the commercial use of biosurfactants are the
Jujjavarapu, S E
core  

Selective production of lipopeptide by Bacillus subtilis in membrane bioreactor [PDF]

, 2009
Bacillus subtilis produit grâce à un mécanisme non-ribosomique trois types de lipopeptides, possédant de nombreuses activités biologiques : les iturines, les surfactines et les fengycines ou plipastatines. La synthèse de ces molécules est le plus souvent
Coutte, François
core  

ACR3 as a Key Regulator Antimicrobial Lipopeptide Synthesis and Efflux in Bacillus velezensis HN-1. [PDF]

Mol Plant Pathol
Shen Y, Wang J, Zeng R, Wang H, Fang Y, Lin Z, Wang Y, Liu W, Xie Q, Jin P, Miao W.   +10 more
europepmc   +1 more source

Short Synthetic Lipopeptides C₁₆-KK-NH₂ and (C₁₀)₂-KKKK-NH₂ Enhance the Activities of Erythromycin and Tetracycline Against ESKAPE Pathogens. [PDF]

Antibiotics (Basel)
Paduszynska MA, Shchuka A, Greber KE.
europepmc   +1 more source