Results 111 to 120 of about 26,449 (239)

A Wagner–Meerwein‐Like Rearrangement Generates a Vinyl Group in the Biosynthesis of the Polychlorinated Lipopeptides Fischerazoles

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
The fischerazoles, unusual cyanobacterial chlorinated lipopeptides are reported. During their biosynthesis, a linear fatty acyl‐acyl carrier protein (ACP) precursor is rearranged through the action of the S‐adenosyl‐methionine (SAM)‐dependent methyltransferase FshF, to generate a pendant vinyl group.
Sandra A. C. Figueiredo, Kathleen Abt, Konrad Viehrig, Peter J. Jervis, Teresa P. Martins, Iñaki Lacomba, Chuhan Li, Daniele Castagnolo, Pedro N. Leão   +8 more
wiley   +2 more sources

Time-dependent dosing of Fe²⁺ for improved lipopeptide production by marine Bacillus megaterium

, 2012
Background: Lipopeptide production is strongly influenced by trace metals. The availability of free Fe2+ in the media throughout the process of fermentation was found to be very critical.
Dhanarajan, Gunaseelan, Kumar, Ramya, Sen, Ramkrishna, Rangarajan, Vivek, Mandal, Mahitosh   +4 more
core   +1 more source

Helicobacter pylori Outer Membrane Vesicles Engage TLR2 Through NapA to Promote Epithelial Association and Inflammatory Signalling

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
ABSTRACT Helicobacter pylori infection is characterized by chronic gastric inflammation driven by persistent activation of innate immune signalling pathways. Outer membrane vesicles (OMVs) released by H. pylori are important mediators of host–pathogen interactions. Although several mechanisms of OMV internalization have been described, how specific OMV‐
Mariaignacia Rubilar, Rosy Brito, Annegrett Palavecino, Joan Villena, Marco Mellado, María I. Silva, Manuel Valenzuela‐Valderrama   +6 more
wiley   +1 more source

Investigation of the Assembly Behavior of an Amphiphilic Lipopeptide at the Liquid Crystal–Aqueous Interface

, 2019
In this article, we designed an amphiphilic lipopeptide molecule, 5(6)-carboxyfluorescein-KKKKKKSKTK-Cys­(C12H25)-OMe (FAM-lipopeptide-C12), and studied its assembly behavior at the 4-cyano-4′-pentylbiphenyl (5CB)-aqueous interface.
Fangyi Li (1566442), Yi Tian (102226), Yongxiang Chen (483293), Xiuxiu Yang (6317015), Zhongqiang Yang (1364157), Suk Fun Tan (6317018), Qing Yu (337275)   +6 more
core   +1 more source

A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor

Pharmacological Research
β-arrestins play pivotal roles in seven transmembrane receptor (7TMR) signalling and trafficking. To study their functional role in regulating specific receptor systems, current research relies mainly on genetic tools, as few pharmacological options are ...
Rebecca L. Brouillette, Christine E. Mona, Michael Desgagné, Malihe Hassanzedeh, Émile Breault, Frédérique Lussier, Karine Belleville, Jean-Michel Longpré, Michel Grandbois, Pierre-Luc Boudreault, Élie Besserer-Offroy, Philippe Sarret   +11 more
doaj   +1 more source

From Rhizosphere to Resistance: Microbe‐Plant Interactions in Eco‐Smart Biocontrol

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Conceptual framework of eco‐smart biocontrol: Root exudates released by plants shape rhizosphere microbial community assembly by selectively recruiting beneficial microorganisms. These microbes suppress phytopathogens through direct mechanisms such as antibiosis, parasitism, enzyme production, and niche competition, while simultaneously activating ...
Shilpy Singh, Varun Kumar Sharma, Dharmsheel Shrivastav, Jayant M. Kushwaha, Manoj Kumar Mishra, Mirza Masroor Ali Beg   +5 more
wiley   +1 more source

Supramolecular Complexes of Ultrashort Cationic Lipopeptides with Cyclodextrins: Improved Selectivity and Therapeutic Potential

Aggregate
In the last decade, the rise of antibiotic resistance has heightened interest in antimicrobial peptides and lipopeptides as promising alternatives to conventional antibiotics because of their lower propensity to develop resistance.
Chiara Bellini, Unai Atxabal, Szilvia Bősze, Orsolya Dobay, Andrea Horváth, Imola Cs. Szigyártó, Tamás Beke‐Somfai, Jesús Jiménez‐Barbero, István Puskás, Kata Horváti   +9 more
doaj   +1 more source

Potential Use of Microbial Surfactant in Microemulsion Drug Delivery System: A Systematic Review

Drug Design, Development and Therapy, 2020
Mandana Ohadi,1 Arash Shahravan,2 Negar Dehghannoudeh,3 Touba Eslaminejad,1 Ibrahim M Banat,4 Gholamreza Dehghannoudeh1,5 1Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran; 2Endodontology ...
Ohadi M, Shahravan A, Dehghannoudeh N, Eslaminejad T, Banat IM, Dehghannoudeh G   +5 more
doaj  

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Untersuchung von Anti‐Glykan‐Antikörpern und Erforschung ihres medizinischen Potenzials mithilfe synthetischer Glykane

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source