Results 31 to 40 of about 24,712 (234)
Sequence of synthetic lipopeptide. [PDF]
, 2019 Sequence of synthetic lipopeptide.
Lvfeng Yuan (3913936) +4 more
core +1 more source
Lipopeptide Pepducins as Therapeutic Agents
, 2021 Pepducins are lipidated peptides that target the intracellular loops of G protein-coupled receptors (GPCRs) in order to modulate transmembrane signaling to internally located effectors. With a wide array of potential activities ranging from partial, biased, or full agonism to antagonism, pepducins represent a versatile class of compounds that can be ...
Michael, Emily +2 more
openaire +3 more sources
AFM Study of Nanoscale Membrane Perturbation Induced by Antimicrobial Lipopeptide C14 KYR
Membranes, 2021 Lipopeptides have been extensively studied as potential antimicrobial agents. In this study, we focused on the C14-KYR lipopeptide, a modified version of the KYR tripeptide with myristic acid at the N-terminus. Here, membrane perturbation of live E. coli
Sawinee Nasompag +7 more
doaj +1 more source
Ultrashort antibacterial and antifungal lipopeptides [PDF]
Proceedings of the National Academy of Sciences, 2006 Host-defense cationic antimicrobial peptides (≈12–50 aa long) play an essential protective role in the innate immune system of all organisms. Lipopeptides, however, are produced only in bacteria and fungi during cultivation, and they are composed of specific lipophilic moieties attached to anionic peptides (six to seven amino acids)
Arik, Makovitzki +2 more
openaire +2 more sources
Structural and Functional Siderophore Remodeling by Enzymatic Delipidation
Angewandte Chemie, EarlyView.A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog +5 more
wiley +2 more sources
Biological control of potato common scab and growth promotion of potato by Bacillus velezensis Y6
Frontiers in Microbiology, 2023 Potato common scab, caused mainly by Streptomyces scabies, causes surface necrosis and reduces the economic value of potato tubers, but effective chemical control is still lacking.
Huan Tao +10 more
doaj +1 more source
Genotoxicity of cationic lipopeptide nanoparticles
Toxicology Letters, 2020 The genotoxicity of cationic lipopeptide nanoparticles (cLPNPs) was evaluated in vivo and in vitro comet assay and the in vivo chromosome aberrations test. In vitro comet assay, human blood cells were exposed to cLPNPs at the concentration of 2.5, 5, 10, 20, 40 and 100 μg/mL.
Aliy K. Zhanataev +7 more
openaire +3 more sources
Adjuvant lipopeptide interaction with model membranes [PDF]
, 1998 The cationic lipohexapeptide Pam3Cys–Ser–(Lys)4 is a synthetic model for the triacylated N-terminal part of bacterial lipoproteins, and it is used as an adjuvant and macrophage activator.
Tocanne, Jean François +6 more
core +1 more source
Angewandte Chemie, EarlyView.The fischerazoles, unusual cyanobacterial chlorinated lipopeptides are reported. During their biosynthesis, a linear fatty acyl‐acyl carrier protein (ACP) precursor is rearranged through the action of the S‐adenosyl‐methionine (SAM)‐dependent methyltransferase FshF, to generate a pendant vinyl group.
Sandra A. C. Figueiredo +8 more
wiley +2 more sources
Self-Assembly of a Catalytically Active Lipopeptide and Its Incorporation into Cubosomes [PDF]
, 2019 The self-assembly and biocatalytic activity of the proline-functionalized lipopeptide PRW-NH-C16 are examined and compared to that of the related PRW–O-C16 lipopeptide, which differs in having an ester linker between the lipid chain and tripeptide ...
Andrea M. Aguilar (2424766) +15 more
core +4 more sources