Results 61 to 70 of about 12,566 (192)
Genotoxicity of cationic lipopeptide nanoparticles
Toxicology Letters, 2020 The genotoxicity of cationic lipopeptide nanoparticles (cLPNPs) was evaluated in vivo and in vitro comet assay and the in vivo chromosome aberrations test. In vitro comet assay, human blood cells were exposed to cLPNPs at the concentration of 2.5, 5, 10, 20, 40 and 100 μg/mL.
Aliy K. Zhanataev +7 more
openaire +3 more sources
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
VIEW, EarlyView.Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source
Lipopeptides as rhizosphere public goods for microbial cooperation
Microbiology SpectrumCyclic lipopeptides (CLPs) are key bioactive secondary metabolites produced by some plant beneficial rhizobacteria such as Pseudomonas and Bacillus. They exhibit antimicrobial properties, promote induced systemic resistance in plants, and support key ...
Augustin Rigolet +7 more
doaj +1 more source
Frontiers in Immunology, 2013 Peptide based vaccines offer several advantages over conventional whole organism or protein approaches by offering improved purity and specificity in inducing immune response. However, peptides alone are generally non-immunogenic.
Mehfuz eZaman +2 more
doaj +1 more source
Frontiers in Microbiology, 2020 Oomycete Phytophthora infestans [(Mont.) de Bary] is the cause of potato late blight, a plant disease which poses a serious threat to our global food security and is responsible for huge economic losses worldwide.
Youyou Wang +5 more
doaj +1 more source
The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1
The FEBS Journal, EarlyView.ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu +2 more
wiley +1 more source
Journal of Fish Diseases, EarlyView.ABSTRACT Disease outbreaks and the associated reliance on antibiotics pose major constraints to the sustainability of modern aquaculture. As regulatory pressures increase and consumer demand shifts toward residue‐free production, diverse biological interventions are gaining prominence as viable alternatives to chemotherapeutics.
Mustafa Öz +5 more
wiley +1 more source
Structure of the lipopeptide antibiotic tsushimycin
Acta Crystallographica Section D Biological Crystallography, 2005 The amphomycin derivative tsushimycin has been crystallized and its structure determined at 1.0 A resolution. The asymmetric unit contains 12 molecules and with 1300 independent atoms this structure is one of the largest solved using ab initio direct methods.
Bunkoczi, G. +2 more
openaire +3 more sources
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
Plant, Cell &Environment, EarlyView.ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Nutrition & Santé, 2016 Since the end of the 20th century, the efforts regarding the environment protection have been increasingly intensified. As most of surfactants used at present arise from the chemical industry, the search for new biological surfactants or biosurfactants ...
Hanen BEN AYED, Moncef NASRI
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